Results 91 to 100 of about 13,188 (213)

Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment

Frontiers in Pharmacology
N-nitrosamines and nitrosamine drug substance related impurities (NDSRIs) became a critical topic for the development and safety of small molecule medicines following the withdrawal of various pharmaceutical products from the market.
Andreas H. Göller, Sandra Johanssen, Adam Zalewski, Verena Ziegler   +3 more
doaj   +1 more source

Garcinia atroviridis pastilles with anti-obesity potential [PDF]

, 2020
Garcinia atroviridis has been used as food seasoning since ancient times. Garcinia atroviridis was reported to contain anti-inflammatories, anti-fungal, antioxidant and anti-obesity properties.
Azeman, Nur Hasnatul Haniemah, Fauzi, Basirah, Harun, Nur Hasanah, Mohamed, Norfatihah, Mohd Adnan, Raudah, Mohd Aripen, Nur Shahirah, Mohd Ghazali, Jamilah, Mohd Ismail, Nurul Izzati   +7 more
core  

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract

The FEBS Journal, Volume 293, Issue 6, Page 1624-1642, March 2026.
Nitrate from food is first converted to nitrite by oral bacteria and then further processed in the intestine. The gut microbiota reduces nitrate and nitrite to ammonia or nitric oxide, preventing the formation of carcinogenic nitrosamines. Our analysis highlights Escherichia coli as a key player in this detoxification process, supported by other ...
Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean‐Lou Christian Michel Dorne, Uwe Deppenmeier   +4 more
wiley   +1 more source

Editorial Perspective: Smoking, vaping and mental health – a perspective on potential causal mechanisms

Journal of Child Psychology and Psychiatry, Volume 67, Issue 3, Page 425-428, March 2026.
This editorial perspective focuses on the complex relationship of cigarette smoking and e‐cigarette use (‘vaping’) with mental health problems. It is challenging to reliably determine the causal nature of these associations because both (e‐)smoking and mental health problems generally arise during adolescence, and both are highly multifactorial in ...
Jorien L. Treur, Jentien M. Vermeulen, Margot P. van de Weijer   +2 more
wiley   +1 more source

Nitrosamines crisis in pharmaceuticals − Insights on toxicological implications, root causes and risk assessment: A systematic review

Journal of Pharmaceutical Analysis
The presence of N-nitroso compounds, particularly N-nitrosamines, in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic effects.
Hemanth P.R. Vikram, Tegginamath Pramod Kumar, Gunjan Kumar, Narasimha M. Beeraka, Rajashree Deka, Sheik Mohammed Suhail, Sandeep Jat, Namitha Bannimath, Gayatiri Padmanabhan, Ravandur S. Chandan, Pramod Kumar, Bannimath Gurupadayya   +11 more
doaj   +1 more source

Risk assessment of chemical substances of safety concern generated in processed meats

Food Science and Human Wellness, 2019
This manuscript is reviewing the presence of substances of safety concern that may be generated in different types of meat products. Such substances include N-nitrosamines that can be generated under certain conditions when using nitrite as preservative,
Mónica Flores, Leticia Mora, Milagro Reig, Fidel Toldrá   +3 more
doaj   +1 more source

The Effect of Turmeric (Curcuma Domestica Val.) Extract on the Histopathological Lesions of Lung Induced by Cigarette Smokes in Wistar Rats [PDF]

, 2015
This present study is aimed to observe and determine the effects of turmeric (Curcuma domestica Val.) extract administration towards the cytotoxicity effect of cigarette smokes in the lungs of Wistar rats.
Herliyani, N. (Novi), Kusumawardani, A. (Agapietta), Milah, N. U. (Nida), Rahmad, L. (laelatul), Sarwendah, K. (Kurniati), Sutrisno, B. (Bambang), Wasito, R. (R), Wuryastuti, H. (Hastari)   +7 more
core   +3 more sources

Impact of Electronic Nicotine Delivery Systems on Oral Mucosa: A Cytopathological and Molecular Study

Journal of Oral Pathology &Medicine, Volume 55, Issue 3, Page 331-339, March 2026.
ABSTRACT Background The packaging and marketing of electronic cigarettes (e‐cigs) often target younger demographics. This study aimed to evaluate gene expression in e‐cig users through exfoliative cytology. Methods Samples were collected from 17 e‐cig users and 10 nonsmokers as controls.
Alba Pérez‐Jardón, Bruna Fernandes do Carmo Carvalho, Cintia Micaela Chamorro‐Petronacci, Maria Dolores Reboiras‐López, Natalia de Carvalho Faria, Renata Falchete do Prado, Mónica Ghislaine Oliveira Alves, Fábio França Vieira e Silva, Maria‐Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Janete Dias Almeida   +10 more
wiley   +1 more source

Review of food toxicological issues associated in rubber products [PDF]

, 2014
Over the centuries, rubber latex gained its popularity in machinery application due to its unique thermal properties, high elasticity and excellent impact resistance.
Chuah, L.A., Hii, C.L., Law, C.L., Ng, Mei Xiang, Ong, S.P.   +4 more
core  

Biokemija kancerogenih tvari u duhanskom dimu [PDF]

, 2019
Duhanski dim je kompleksna smjesa raznih vrsta spojeva, od kojih su mnoge kancerogene, što može biti posljedica genotoksičnosti, citotoksičnosti ili uzrokovanja raznih upala. Većina karcinogena je stabilna i nereaktivna, pa ulaskom u organizam dolazi do
Inkret, Suzana
core   +2 more sources