Results 21 to 30 of about 1,636 (167)
Effect of celery powder as an alternative nitrite source on some quality properties and nitrosamine formation in sucuk [PDF]
This study aimed to determine the effects of celery powder (nitrate converted to nitrite) and cooking time on the formation of nitrosamine in sucuk. The microbiological and physicochemical properties were also investigated.
Zeynep Feyza YILMAZ ORAL
doaj +1 more source
Suppressive effect of molybdenum on hepatotoxicity of N-nitrosodiethylamine in rats
In order to elucidate the preventive mechanism of molybdenum (Mo) against carcinogenesis of N-nitroso compounds, the effects of in vivo Mo-pretreatment on N-nitrosodiethylamine (NDEA)-induced hepatotoxicity in rats were examined. Effects of in vitro Mo-pretreatment on NDEA-induced DNA strand breaks and fluctuation of the cytosolic free Ca levels in rat
T, Koizumi +7 more
openaire +5 more sources
The global burden of hepatocellular carcinoma is increasing; actually, it is estimated as 750,000 new cases annually. This study was initiated to emphasize the possibility that gallic acid could alleviate hepatocarcinogenesis in vivo .
Hadeer A Aglan +3 more
doaj +1 more source
Carvacrol attenuates N-nitrosodiethylamine induced liver injury in experimental Wistar rats
Carvacrol is a main constituent in the essential oils of countless aromatic plants including Origanum Vulgare and Thymus vulgari, which has been assessed for substantial pharmacological properties.
Balan Rajan +3 more
doaj +1 more source
Hepatocellular carcinoma (HCC) is a common type of liver cancer and is a leading cause of death worldwide. Signal transducer and activator of transcription 3 (STAT3) is involved in HCC progression, migration, and suppression of apoptosis.
Noura M. Darwish +6 more
doaj +1 more source
Presence of nitrosamine impurities in medicinal products
In 2018, some sartan medicinal products were reported to be contaminated with nitrosamine compounds, which are potent mutagenic carcinogens. Two nitrosamines received particular attention: N -nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA ...
Sedlo Ilijana +2 more
doaj +1 more source
HEPATOPROTECTIVE EFFECTS OF POMEGRANATE AND APPLE JUICES AGAINST N-NITROSODIETHYLAMINE- INDUCED HEPATOCELLULAR CARCINOMA IN MALE RATS [PDF]
Liver cancer represents a complex and fatal malignancy derived primarily due to oxidative stress and inflammation; it is the second most prevalent cause of death in underdeveloped and developing countries.
Dr. Amr A. Rezq +3 more
doaj +1 more source
Determination of dietary exposure and extraction efficiency of nitrosamine from cooked meat
Meat products are claimed to be a source of carcinogenic nitrosamines (NAs) exposure in food. In this study, dietary exposure of six nitrosamines: N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR), N ...
Abu Tareq Mohammad Abdullah +4 more
doaj +1 more source
An Enhanced Metabolization Protocol for In Vitro Genotoxicity Assessment of N-Nitrosamines in Mammalian Cells. [PDF]
ABSTRACT N‐Nitrosamines (NAs) are probable human carcinogens and were detected as impurities in pharmaceuticals, which led to a concern for human health. NAs require metabolic activation before they become mutagenic, and not all NAs are mutagenic since their reactivity is related to their structure.
Geijer ME +4 more
europepmc +2 more sources
N-Nitrosodiethylamine (NDEA) is a nitrosamine derivative with carcinogenic and mutagenic properties which can be found in tobacco smoke, meat and various food products.
Emeka Eze Joshua Iweala +2 more
doaj +1 more source

