Results 211 to 220 of about 28,700 (263)

Local Protein Synthesis at Synapses: A Driver for Synapse Diversification

Journal of Neurochemistry, Volume 169, Issue 11, November 2025.
Local protein synthesis is abundant in neuronal processes. This localized translation of mRNA is believed to allow neurons to rapidly modify synaptic strength in response to activity. We review mechanisms guiding mRNA transport into dendrites and axons, emphasizing their selective recruitment for translation during synaptic plasticity.
Ezgi Daskin, Stanley Van, Anne‐Sophie Hafner   +2 more
wiley   +1 more source

N6-methyladenosine RNA landscape in the aged mouse hearts. [PDF]

Front Cardiovasc Med
Jing X, Li Y, Liao Z, Wu JY, Xu ZY, Yang ZP, Mo HL, Xu S, Liu X, Wu Z, Tao J, Xiong XD.   +11 more
europepmc   +1 more source

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5 [PDF]

, 2015

core   +1 more source

The role of post‐translational modifications in the dynamics of cytoplasmic biomolecular condensates in plants

New Phytologist, Volume 248, Issue 4, Page 1692-1699, November 2025.
Summary Cytoplasmic biomolecular condensates are membrane‐less structures important for cell homeostasis, especially during stress conditions. These aggregates concentrate RNA, protein, and metabolites during a wide variety of stresses. The formation of cytoplasmic biomolecular condensates was studied extensively in plants, revealing many key actors ...
Margaux Legoux, Jean‐Philippe Reichheld, Rémy Merret   +2 more
wiley   +1 more source

Identification and immune characteristics of N6-methyladenosine related ferroptosis-related genes in intervertebral disc degeneration. [PDF]

Sci Rep
Che Z, Chen R, Li M, Liao Z, Wang K, Yao D, Liang Y, Li Y, Wen G, Xing T, Su K, Liang C, Huang L, Zhao Q.   +13 more
europepmc   +1 more source

Interaction of the intestinal cytokines-JAKs-STAT3 and 5 axes with RNA N6-methyladenosine to promote chronic inflammation-induced colorectal cancer

Nardana Esmaeili, Ahmed Bakheet, William Tse, Shujun Liu, Xiaonan Han   +4 more
openalex   +1 more source

Genetics of Common Obesity in Children and Adolescents

Annals of the New York Academy of Sciences, Volume 1553, Issue 1, Page 34-49, November 2025.
Abstract Childhood obesity is a multifactorial public health problem worldwide. Genetic variation influences the predisposition to develop obesity at early stages of life. Childhood obesity may be classified as syndromic, monogenic, or polygenic depending on the genetic component.
Guadalupe León‐Reyes, Francisco J. López Alavez, Maria Elizabeth Tejero   +2 more
wiley   +1 more source

N6-methyladenosine in cervical carcinogenesis: Mechanistic insights and therapeutic perspectives (Review). [PDF]

Oncol Lett
Xu M, Yang F, Chen H, Jiang F.
europepmc   +1 more source

Epitranscriptomic reprogramming in response to low CO2 stress and m6A engineering to enhance biomass production in Nannochloropsis oceanica

The Plant Journal, Volume 124, Issue 3, November 2025.
Significance Statement Dynamic N6‐adenine methylation (m6A) regulates CO2‐responsive gene expression in Nannochloropsis oceanica. Genome editing of methylases NoMTA and NoMTB triggers m6A reprogramming, and CRISPR/dCas13‐based m6A engineering modulates stress tolerance and biomass production, unveiling an epitranscriptomic mechanism in microalgae ...
Han Zhu, Yikai Wu, Meng Feng, Lingyu Ouyang, Hang Su, Li Wei   +5 more
wiley   +1 more source

Correction to 'Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction'. [PDF]

Nucleic Acids Res
europepmc   +1 more source