Results 31 to 40 of about 46,730 (259)
, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
, 2023 Supplemental material, sj-doc-1-jbm-10.1177_03936155231184908 for Prognostic significance of N6-methyladenosine-modified related chemotransferase METTL3 in gastric carcinoma: Evidence from meta-analysis by Chenglou Zhu, Qiong Wu, Yan Xu, Jichun Ma ...
Junhong Wang (2460004) +7 more
core +1 more source
Functions of N6-methyladenosine and its role in cancer [PDF]
Molecular Cancer, 2019 AbstractN6-methyladenosine (m6A) is methylation that occurs in the N6-position of adenosine, which is the most prevalent internal modification on eukaryotic mRNA. Accumulating evidence suggests that m6A modulates gene expression, thereby regulating cellular processes ranging from cell self-renewal, differentiation, invasion and apoptosis.
Liuer He +5 more
openaire +3 more sources
, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
Frontiers in Medicine, 2021 Purpose: To comprehensively analyze N6-methyladenosine modification patterns in bladder tumors and to further systematically explore the inherent relationships between these modification patterns and multiomic tumor characteristics.Materials and Methods:
Jingchao Liu +17 more
doaj +1 more source
N6-methyladenosine marks primary microRNAs for processing [PDF]
Nature, 2015 The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-miRNAs) by the microprocessor complex, composed of the RNA-binding protein DGCR8 and the type III RNase DROSHA. This initial event requires recognition of the junction between the stem and the flanking single-stranded RNA of the pri-miRNA hairpin by DGCR8 followed
Alarcón, Claudio R +4 more
openaire +6 more sources
Role of N6-methyladenosine Modification in Cardiac Remodeling [PDF]
Frontiers in Cardiovascular Medicine, 2022 Cardiac remodeling is the critical process in heart failure due to many cardiovascular diseases including myocardial infarction, hypertension, cardiovascular disease and cardiomyopathy. However, treatments for heart failure focusing on cardiac remodeling show relatively limited effectiveness.
ManTing Choy +11 more
openaire +3 more sources
, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
Experimental Hematology & Oncology, 2023 Background N6-methyladenosine (m6A) is a prevalent modification of mRNA and is known to play important roles in tumorigenesis in many types of cancer. The function of N6-methyladenosine (m6A) RNA methylation depends on a variety of methyltransferases and
Weijian Wang +9 more
doaj +1 more source