Results 41 to 50 of about 53,902 (279)

Table_7_The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1.XLSX

, 2021
The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439), Yue Shi (128342), Weimin Ci (4459504), Yanliang Dou (11472436), Yu Xiao (150812), Mingxin Zhang (4898947), Jie Qi (53195), Jianye Zhang (430972)   +7 more
core   +1 more source

Correction to "IGF2BP3-Dependent N6-Methyladenosine Modification of USP49 Promotes Carboplatin Resistance in Retinoblastoma by Enhancing Autophagy via Regulating the Stabilization of SIRT1". [PDF]

Kaohsiung J Med Sci
The Kaohsiung Journal of Medical Sciences, EarlyView.
europepmc   +2 more sources

Image_2_Establishment of Prognostic Signatures of N6-Methyladenosine-Related lncRNAs and Their Potential Functions in Hepatocellular Carcinoma Patients.tif

, 2022
N6-methyladenosine (m6a)-related mRNAs and lncRNAs have been explored for their functions in several cancers. The present study aimed to identify potential signatures of m6a-related lncRNAs in hepatocellular carcinoma (HCC).
Zhejun Deng (12791090), Xianbin Wu (12791087), Lixing Pang (12791096), Xiaomin Liao (11147295), Haixing Jiang (8507154), Nanfang Qu (8507145), Xianxian Ruan (12791093), Shanyu Qin (12259896), Xiaoyan Shi (156294)   +8 more
core   +1 more source

Image_1_Establishment of Prognostic Signatures of N6-Methyladenosine-Related lncRNAs and Their Potential Functions in Hepatocellular Carcinoma Patients.tif

, 2022
N6-methyladenosine (m6a)-related mRNAs and lncRNAs have been explored for their functions in several cancers. The present study aimed to identify potential signatures of m6a-related lncRNAs in hepatocellular carcinoma (HCC).
Zhejun Deng (12791090), Xianbin Wu (12791087), Lixing Pang (12791096), Xiaomin Liao (11147295), Haixing Jiang (8507154), Nanfang Qu (8507145), Xianxian Ruan (12791093), Shanyu Qin (12259896), Xiaoyan Shi (156294)   +8 more
core   +1 more source

UPLC-MS/MS method for simultaneously determining nucleosides and methyl-nucleosides in liver mRNA of Epimedin C-induced liver injury mouse model

Chinese Medicine, 2021
Background Epimedin C, one of the main active ingredients of Epimedium, has been reported to have potential hepatotoxicity. However, the mechanism of Epimedin C-induced liver injury has not been studied.
Zhizhen Song, Zeyun Li, Xueqian Wen, Ruijuan Liu, Xin Tian   +4 more
doaj   +1 more source

RNA Sequencing Reveals the Regulation of Betaine on Chicken Myogenesis

Animals, 2022
Betaine is trimethylglycine and a universal methyl donor which could provide methyl and glycine for cells and animals. As a new star in epigenetics, N6-Methyladenosine has been reported to regulate multiple biological activities, but the regulatory ...
Zhijun Wang, Danfeng Cai, Xing Ju, Kan Li, Sisi Liang, Meixia Fang, Qinghua Nie   +6 more
doaj   +1 more source

Data_Sheet_5_Comprehensive Analysis of N6-methyladenosine Modification Patterns Associated With Multiomic Characteristics of Bladder Cancer.ZIP

, 2021
Purpose: To comprehensively analyze N6-methyladenosine modification patterns in bladder tumors and to further systematically explore the inherent relationships between these modification patterns and multiomic tumor characteristics.Materials and Methods:
Haoran Xia (7062632), Jianye Wang (453856), Zhengtong Lv (10146227), Wei Zhang (405), Lingfeng Meng (2576632), Meng Wu (191457), Yaoguang Zhang (746651), Jianlong Wang (438075), Jiawen Wang (350508), Jingchao Liu (2051245)   +9 more
core   +1 more source

Role of N6-methyladenosine modification in cancer

Current Opinion in Genetics & Development, 2018
As the most abundant internal modification in eukaryotic messenger RNAs identified, N6-methyladenosine (m6A) has been shown recently to play essential roles in various normal bioprocesses. Evidence is emerging that m6A modification and its regulatory proteins also play critical roles in various cancers including leukemia, brain tumor, breast cancer and
Xiaolan, Deng, Rui, Su, Xuesong, Feng, Minjie, Wei, Jianjun, Chen   +4 more
openaire   +3 more sources

The N6-Methyladenosine RNA modification in pluripotency and reprogramming [PDF]

Current Opinion in Genetics & Development, 2017
Chemical modifications of RNA provide a direct and rapid way to manipulate the existing transcriptome, allowing rapid responses to the changing environment further enriching the regulatory capacity of RNA. N6-Methyladenosine (m6A) has been identified as the most abundant internal modification of messenger RNA in eukaryotes, linking external stimuli to ...
Francesca, Aguilo, Martin J, Walsh
openaire   +2 more sources

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

Nature Communications, 2021
The demethylase FTO was shown to remove on N6-methyladenosine (m6A) and N6, 2’-O-dimethyladenosine (m6Am) modifications on RNAs. Here the authors show that FTO impedes cancer stem cell-like abilities in colorectal cancer cells through its m6Am ...
Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean-Jacques Vasseur, Julie Pannequin, Francesca Aguilo, Evelyne Lopez-Crapez, Christophe Hirtz, Eric Rivals, Amandine Bastide, Alexandre David   +21 more
doaj   +1 more source