Results 121 to 130 of about 16,968 (203)

CTSS and CD53: Emerging m6A methylation markers in diabetic kidney disease pathogenesis and their clinical implications

BMC Nephrology
Objective Diabetic kidney disease (DKD) is increasingly recognized as a leading cause of chronic kidney disease (CKD) worldwide. Although N6-methyladenosine (m6A) mRNA modification is abundant in eukaryotes, its specific contribution to DKD pathogenesis ...
Meng Leilei, Huang Bin, Li Rui, Wenjie Wen   +3 more
doaj   +1 more source

Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing

Plant, Cell &Environment, Volume 49, Issue 7, Page 4000-4014, July 2026.
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang, Zhixia Xiao, Ailin Liu, Dongpeng Ren, Shengjie Chen, Hanxue Zhang, Li Zhang, Zhili Wang, Jun Yang, Hon‐Ming Lam   +9 more
wiley   +1 more source

m6A demethylase FTO promotes the progression of abdominal aortic aneurysm through PDK4-mediated apoptosis

Scientific Reports
N6-methyladenosine (m6A) is one of the most abundant methylation modifications in mRNA, regulating different stages of mRNA metabolism, including folding, maturation, export, translation, and decay.
Wei Gong, Xue Yang, Ning Fan, Han Wang, Shengjie Fu, Yu Tian, Lei Li   +6 more
doaj   +1 more source

Engineering Bisubstrates to Target m6Am RNA Methyltransferases: Synthesis and Computational Studies

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
Use of the convertible nucleoside approach to synthesize m6Am RNA methyltransferase bisubstrates. This methodology allows for the introduction of modifications on the SAM analog moiety and the RNA substrate part, including the introduction of a cap analog by click chemistry.
Yoann Colas, Laurent Le Corre, Mélanie Ethève‐Quelquejeu, Emmanuelle Braud   +3 more
wiley   +1 more source

Recent Advances in the Mutual Regulation of m6A Modification and Non-Coding RNAs in Atherosclerosis

International Journal of General Medicine
Yanlu Wang, Sisi Ling, Hao Feng, Junkai Hua, Zhiyu Han, Renjie Chai Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, 510260, People’s Republic of ChinaCorrespondence: Renjie Chai ...
Wang Y, Ling S, Feng H, Hua J, Han Z, Chai R   +5 more
doaj  

N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases. [PDF]

J Innate Immun, 2023
Teng Y, Yi J, Chen J, Yang L.
europepmc   +1 more source

N6-methyladenosine (m6A) methylation in adipose tissue: role, regulation, and therapeutic potential. [PDF]

Cell Mol Life Sci
Liu Q, Peng WQ, Guo L.
europepmc   +1 more source

N6-methyladenosine (m6A) modification in osteosarcoma: expression, function and interaction with noncoding RNAs - an updated review. [PDF]

Epigenetics, 2023
Zhang Y, Xu Y, Bao Y, Luo Y, Qiu G, He M, Lu J, Xu J, Chen B, Wang Y.   +9 more
europepmc   +1 more source

Mechanism of N6-methyladenosine (m6A)-mediated upregulation of LINC00958 in the growth of cervical cancer. [PDF]

Front Oncol
Li Y, Liu Z, Jin H.
europepmc   +1 more source

m6AConquer: a consistently quantified and orthogonally validated database for the N6-methyladenosine (m6A) epitranscriptome. [PDF]

Nucleic Acids Res
Zhao X, Ye H, He D, Liu H, Li T, Rigden DJ, Wei Z.   +6 more
europepmc   +1 more source