Results 141 to 150 of about 54,300 (231)
Understanding exosomes in regenerative dentistry
Periodontology 2000, EarlyView.Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
The Journal of Physiology, EarlyView.Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
The Plant Genome, Volume 19, Issue 4, December 2026.Abstract 5‐Methylcytidine (m5C) modifications play a critical role in RNA metabolism. TRM4B (tRNA‐specific methytransferase 4B) is the only known component of the plant m5C machinery that mediates mRNA (messenger RNA) methylation. To date, no regulators governing site‐specific m5C modifications have been identified, apart from several degenerated ...
Zedi Feng +6 more
wiley +1 more source
Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress
Plant, Cell &Environment, Volume 49, Issue 11, Page 8437-8453, November 2026.ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee +5 more
wiley +1 more source
The implications of N6-methyladenosine (m6A) modification in esophageal carcinoma. [PDF]
Mol Biol Rep, 2023 He C +7 more
europepmc +1 more source
Influence of N6-methyladenosine (m6A) modification on cell phenotype in Alzheimer's disease. [PDF]
PLoS One, 2023 Ni P, Pan K, Zhao B.
europepmc +1 more source
Molecular Oncology, Volume 20, Issue 10, Page 2410-2423, October 2026.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Recent Advances in the Mutual Regulation of m6A Modification and Non-Coding RNAs in Atherosclerosis
International Journal of General MedicineYanlu Wang, Sisi Ling, Hao Feng, Junkai Hua, Zhiyu Han, Renjie Chai Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, 510260, People’s Republic of ChinaCorrespondence: Renjie Chai ...
Wang Y +5 more
doaj
CCNE1: A Cell Cycle Regulator That Influences Tumor Progression
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan +6 more
wiley +1 more source