Results 141 to 150 of about 17,129 (229)

m6AConquer: a consistently quantified and orthogonally validated database for the N6-methyladenosine (m6A) epitranscriptome. [PDF]

Nucleic Acids Res
Zhao X, Ye H, He D, Liu H, Li T, Rigden DJ, Wei Z.   +6 more
europepmc   +1 more source

Synthesis of DNA Building Blocks With Aminonaphthalimides and Cyanovinylenes as Uncharged Fluorophores: Fluorescent Readout From Turn‐On to Red‐Shift

European Journal of Organic Chemistry, Volume 29, Issue 29, 7 August 2026.
DNA architectures with aminonaphthalimides and cyanovinylenes as base surrogates form interstrand and intrastrand dimers showed that can be used as nucleic acid‐sensitive probes by their fluorescence turn‐on and red‐shift as readouts. The fluorescence turn‐on was tested by probing N6‐methyl‐2’‐deoxyadenosine (m6A) in DNA.
Jan Kunzmann, Anna‐Lena Ruopp, Hans‐Achim Wagenknecht   +2 more
wiley   +1 more source

m6AHD: a new framework for identifying abnormal N6-methyladenosine (m6A) in heart diseases based on sequencing features. [PDF]

Front Genet
Lu J, Li Y, Hong Y, Liao D, Fang G.
europepmc   +1 more source

RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition. [PDF]

Cell Death Dis
Ross SE, Holliday H, Wang E, Zeraati M, Tsoli M, Ziegler DS, Dinger ME.   +6 more
europepmc   +1 more source

Retracted: The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, Volume 13, Issue 45, 13 August 2026.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

Emerging role of N6-methyladenosine (m6A) epitranscriptomic changes in adult anxiety after adolescent alcohol exposure. [PDF]

Neuropharmacology
Malovic E, Tandukar J, Zhang H, Venkareddy LK, Gao R, Pandey SC.   +5 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, Volume 13, Issue 43, 3 August 2026.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Epigenetic Regulation of Bone Homeostasis in Osteoporosis: Mechanisms, Evidence Gaps, and Translational Prospects

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Osteoporosis arises from an imbalance among osteoblast‐mediated bone formation, osteoclast‐mediated bone resorption, and osteocyte‐directed mechanosensory control, but the molecular events that connect aging, hormonal change, inflammation, and mechanical unloading to bone loss remain incompletely resolved.
Minjuan Du, Leisheng Wang
wiley   +1 more source

N6-methyladenosine (m6A) dysregulation contributes to network excitability in temporal lobe epilepsy. [PDF]

JCI Insight
Mathoux J, Wilson MM, Srinivas S, Litovskich G, Villalba Benito L, Tran C, Kesavan J, Harnett A, Auer T, Sanz-Rodriguez A, Kh A E Alkhayyat M, Sullivan M, Liu Z, Huang Y, Lacey A, Delanty N, Cryan J, Brett FM, Farrell MA, O'Brien DF, Casillas-Espinosa PM, Jimenez-Mateos EM, Glennon JC, Canavan M, Henshall DC, Brennan GP.   +25 more
europepmc   +1 more source