Results 161 to 170 of about 16,968 (203)

Effects of N⁶-Methyladenosine (m⁶A) and 5-Methylcytosine (m⁵C) Modifications in the Guide Region of CRISPR RNA on Cas12a Nuclease Activity. [PDF]

Bioconjug Chem
Pandit B, Hanson E, Dagci H, Yang Q, Yigit MV, Royzen M.   +5 more
europepmc   +1 more source

Structural Analysis of Virus Regulatory N6-Methyladenosine (m6A) Machinery of the Black Flying Fox (Pteropus alecto) and the Egyptian Fruit Bat (Rousettus aegyptiacus) Shows Evolutionary Conservation Amongst Mammals. [PDF]

Genes (Basel)
Nasr A, Copeland N, Munir M, Munir M.
europepmc   +1 more source

RNA methylation patterns, immune characteristics, and autophagy-related mechanisms mediated by N6-methyladenosine (m6A) regulatory factors in venous thromboembolism. [PDF]

BMC Genomics
Zhang D, Fu W, Zhu S, Pan Y, Li R.
europepmc   +1 more source

N6-methyladenosine (m6A)-circHECA from secondary hair follicle of cashmere goats: identification, regulatory network and expression regulated potentially by methylation of its host gene promoter. [PDF]

Anim Biosci
Shen J, Hui T, Bai M, Fan Y, Zhu Y, Zhang Q, Xu R, Zhang J, Wang Z, Zheng W, Bai W.   +10 more
europepmc   +1 more source

When animal viruses meet N⁶-methyladenosine (m⁶A) modifications: for better or worse? [PDF]

Vet Res
Wang W, Jin Y, Xie Z, He M, Li J, Wang Z, Ma S, Zhang W, Tong J.   +8 more
europepmc   +1 more source

Global mapping of RNA N⁶-methyladenosine (m⁶A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity. [PDF]

Biomark Res
Rønningen T, Zeng Y, Dahl MB, Wang J, Visnovska T, Tannæs TM, la Cour Poulsen L, Cayir A, Svensson SIA, Svanevik M, Hertel JK, Hjelmesæth J, Kristinsson JA, Mala T, Blüher M, He HH, Valderhaug TG, Böttcher Y.   +17 more
europepmc   +1 more source

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N6‐methyladenosine (m6A) modification in gynecological malignancies

Journal of Cellular Physiology, 2022
AbstractN6‐methyladenosine (m6A) modification is one of the most abundant modifications in eukaryotic mRNA, regulated by m6A methyltransferase and demethylase. m6A modified RNA is specifically recognized and bound by m6A recognition proteins, which mediate splicing, maturation, exonucleation, degradation, and translation.
Ning Liu
exaly   +3 more sources

N6-methyladenosine (m6A) methylation in kidney diseases: Mechanisms and therapeutic potential

Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2023
The N6-methyladenosine (m6A) modification is regulated by methylases, commonly referred to as "writers," and demethylases, known as "erasers," leading to a dynamic and reversible process. Changes in m6A levels have been implicated in a wide range of cellular processes, including nuclear RNA export, mRNA metabolism, protein translation, and RNA splicing,
Hangyu Ji, Cunqing Yang, Linlin Jiang
exaly   +3 more sources

Effect of circular RNAs and N6-methyladenosine (m6A) modification on cancer biology

Biomedicine and Pharmacotherapy, 2023
N6-methyladenosine (m6A), as the most abundant and well-known RNA modification, has been found to play an important role in cancer. Circular RNAs (circRNAs) are a class of single-stranded covalently closed RNA molecules generated by the reverse splicing process.
Gong Zhang, Junhui Hou, Kefeng Wang
exaly   +3 more sources

N6‐methyladenosine (m6A) Modification in Preeclampsia

Reproductive Sciences, 2023
Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of preeclampsia. Advances in m6A sequencing have revealed the molecular mechanism and importance of m6A modification.
Tingting Zhang, Ziyan Jiang, Nana Yang, Zhiping Ge, Qing Zuo, Shiyun Huang, Lizhou Sun   +6 more
openaire   +2 more sources