Results 161 to 170 of about 17,129 (229)

A New Approach to Manufacturing Oral Drug Delivery Systems via Selective Laser Sintering With Water‐Insoluble Biocompatible Thermoplastic Polymers: Gaps, Risks, Challenges, and Future Directions

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 8, August 2026.
Selective laser sintering enables the fabrication of personalized oral drug delivery systems using biocompatible thermoplastics such as PA12 and polyethylene, offering controlled release and structural precision. However, high‐energy processing introduces safety concerns, including emissions and micro‐ and nanoplastic formation.
Klara Dorożyńska   +4 more
wiley   +1 more source

Glucose Transporter 1 in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai   +3 more
wiley   +1 more source

A conserved role of the N6-methyladenosine (m6A) modification in spermatogenesis

open access: yesReproduction and Breeding
Ayla Sinclair, Antonio Rockwell
openaire   +1 more source

Acute Dietary Zinc Deficiency Impairs Sperm Motility but Not Gonadal mRNA Methylation in Mice

open access: yesMolecular Reproduction and Development, Volume 93, Issue 8, August 2026.
Male and female mice were fed a control or zinc‐deficient diet for 6 days. In males, cauda epididymal sperm were analyzed for number, motility, and morphology, and testes were assessed by histology, while m6A mRNA methylation was measured in the testis and liver of males and the ovary and liver of females.
Ngozi O. Ibadin, Francisco J. Diaz
wiley   +1 more source

MAPK Inhibitor‐Tolerant Persister Cells in Melanoma: Mechanisms and Therapeutic Vulnerabilities

open access: yesCancer Science, Volume 117, Issue 8, Page 2050-2063, August 2026.
Melanoma response to MAPK inhibition progresses from drug‐sensitive cells to drug‐tolerant persister states, which enable survival through adaptive signaling, metabolic rewiring, and phenotypic plasticity. These persister cells serve as an intermediate reservoir from which resistant tumors ultimately emerge. ABSTRACT Though major advancements have been
Bhoomi Shah   +3 more
wiley   +1 more source

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