Results 121 to 130 of about 55,457 (267)

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma, Hirotaka Tomiyasu, Mari Takamiya, Yuko Goto‐Koshino, Atsushi Tsukamoto, Makoto Bonkobara, Masaru Okuda   +6 more
wiley   +1 more source

Nab-Paclitaxel for Relapsed AIDS-Related Kaposi Sarcoma -A Case Report

Lele Yu, Binhai Zhang, Hu Wan Department II of Infectious Diseases, Hangzhou Xixi Hospital, Hangzhou Sixth People’s Hospital, Hangzhou, Zhejiang, 310023, People’s Republic of ChinaCorrespondence: Hu Wan, Email yll8024@126.comIntroduction: Kaposi sarcoma (
Yu L, Wan H, Zhang B
core  

Table_1_nab-Paclitaxel-Based Therapy in Underserved Patient Populations: The ABOUND.70+ Study in Elderly Patients With Advanced NSCLC.docx

, 2018
The phase 4 ABOUND.70+ trial assessed the safety and efficacy of nab-paclitaxel/carboplatin continuously or with a 1-week break between cycles in elderly patients with advanced non-small cell lung cancer (NSCLC).
Matei P. Socoteanu (5546894), Teng J. Ong (5546897), Manuel Modiano (5546885), Kartik Konduri (5546879), Eric C. Anderson (3073926), Jonathan W. Goldman (5546906), on behalf of the ABOUND.70+ Investigators (5546903), Daniel E. Haggstrom (5546888), Edward S. Kim (2183847), Corey J. Langer (5546882), Robert M. Jotte (5546891), Tymara Berry (5546843), Jared Weiss (5546900), Christopher Dakhil (5546876), Alexandra Sanford (5546849), Katayoun Amiri (5546870), David A. Smith (2577271)   +16 more
core   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Comparison of Efficacy Between Nab-Paclitaxel or Docetaxel Combined with Carboplatin as Neoadjuvant Therapy for HER2-Positive Breast Cancer

Zhongliu Fangzhi Yanjiu
ObjectiveTo compare the efficacy of trastuzumab plus pertuzumab (HP) combined with either nab-paclitaxel plus carboplatin or docetaxel plus carboplatin as neoadjuvant therapy for HER2-positive breast cancer in real-world clinical practice ...
Xin HAO, Chongzhu HU, Ruixue YUE, Tianpei MIAO, Zhong LI   +4 more
doaj   +1 more source

Pancreatic Cancer—Advances in the Last 50 Years

World Journal of Surgery, EarlyView.
S. George Barreto, Anirban Maitra, Eileen M. O'Reilly, Dushyant Sahani, Richard Zheng, Charles J. Yeo   +5 more
wiley   +1 more source

Small‐Bowel Impaction Caused by Mechanical Interlocking Between Duodenal Metal and Biliary Plastic Stents

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Duodenal self‐expandable metal stents (SEMS) are widely used to treat malignant gastric outlet obstruction (GOO). However, stent migration is a well‐known complication. We report a rare case of small‐bowel impaction caused by the migration of a duodenal SEMS with a biliary plastic stent (PS).
Shinsuke Otagiri, Ryo Sugiura, Masataka Wada, Asako Nomura, Hiroki Egami, Kento Wakabayashi, Kenta Fujihata, Takehiko Katsurada, Satoshi Hirano, Naoya Sakamoto   +9 more
wiley   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, Volume 159, Issue 2, Page 460-466, 15 July 2026.
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Nab-Paclitaxel: A Novel Formulation of Taxane for Treatment of Breast Cancer

, 2010
Breast cancer is the most common type of cancer diagnosed in women. Anthracyclines and taxanes are the most active and widely used chemotherapeutic agents in the treatment of both early-stage and advanced breast cancer.
Vivek Roy, Prakash Vishnu
core   +1 more source

Cervical Metastasis From Primary Breast Carcinoma: A Case Report and Review of Extragenital Tumors Involving the Uterine Cervix

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cervical metastases from breast carcinoma should be considered in the differential diagnosis of uterine lesions in patients with prior breast cancer. Re‐biopsy is essential to detect receptor discordance (ER/PR up to 29%) and guide therapy. GCDFP‐15, mammaglobin, and GATA3 confirm mammary origin.
Mario Assenza, Adele Zappalà, Armando Nallbani, Jacopo Wabersich   +3 more
wiley   +1 more source