Results 111 to 120 of about 17,658 (223)
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
ABSTRACT This case reports rare cervical villoglandular adenocarcinoma metastasizing to the ovary with a deceptive borderline‐like morphology. Diagnosis relied on matching immunohistochemistry and HPV16 DNA detection in both sites. The patient underwent surgery and chemoradiotherapy, remaining recurrence‐free.
Ni Ma +4 more
wiley +1 more source
Raja Mudad,1 Manish B Patel,2 Sandra Margunato-Debay,2 David Garofalo,3 Lincy S Lal4 1University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, Hollywood, FL, USA; 2Celgene Corporation, Summit, NJ, USA; 3Cardinal Health ...
Mudad R +4 more
doaj
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko +31 more
wiley +1 more source
ABSTRACT Introduction Situs inversus totalis complicates minimally invasive surgery, and simultaneous robotic surgery for tumors of different organs is particularly challenging. Case Presentation A 72‐year‐old man with situs inversus totalis receiving androgen blockade for prostate cancer developed a 40‐mm muscle‐invasive bladder tumor undetected on ...
Takaharu Hamada +9 more
wiley +1 more source
Cesare Gridelli,1 Tianlei Chen,2 Amy Ko,2 Mary E O’Brien,3 Teng Jin Ong,4 Mark A Socinski,5 Pieter E Postmus6 1Division of Medical Oncology, S. G.
Gridelli C +6 more
doaj
γ‐T3 Increases the Sensitization of Gastric Cancer Cells to OXA by a Regulation of ARHGAP29
γ‐T3 combined with oxaliplatin (OXA) inhibited the proliferation of gastric cancer cells by induction autophagy via ARHGAP29/GSK‐3β/β‐Catenin pathways. γ‐T3 combined with low‐dose of OXA could exert synergistic effects on induction autophagy‐related gastric cancer cell death, which is partially mediated by down‐regulation of the ARHGAP29/GSK‐3β/β ...
Hao Zhu +11 more
wiley +1 more source
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen +3 more
wiley +1 more source
Atherosclerosis: From Pathogenesis to Therapeutic Interventions
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou +9 more
wiley +1 more source

