Results 91 to 100 of about 7,945,802 (238)

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Expression of the Arabidopsis redox-related LEA protein, SAG21 is regulated by ERF, NAC and WRKY transcription factors

Scientific Reports
SAG21/LEA5 is an unusual late embryogenesis abundant protein in Arabidopsis thaliana, that is primarily mitochondrially located and may be important in regulating translation in both chloroplasts and mitochondria.
Kelly V. Evans, Elspeth Ransom, Swapna Nayakoti, Ben Wilding, Faezah Mohd Salleh, Irena Gržina, Lieselotte Erber, Carmen Tse, Claire Hill, Krzysztof Polanski, Alistair Holland, Sherien Bukhat, Robert J. Herbert, Barend H. J. de Graaf, Katherine Denby, Vicky Buchanan-Wollaston, Hilary J. Rogers   +16 more
doaj   +1 more source

Carcinoembryonic Antigen Messenger RNA in Pelvic Lavage Fluid Predicts Local Recurrence After Curative‐Intent Resection of Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Pelvic lavage carcinoembryonic antigen (CEA) mRNA was quantified in 178 patients undergoing curative‐intent resection for rectal cancer. Positive pelvic lavage CEA mRNA was significantly associated with local recurrence and provided additional prognostic information beyond circumferential resection margin (CRM) status.
Hiroyuki Asai, Yushi Yamakawa, Kazuyoshi Shiga, Shuhei Uehara, Akira Kato, Takuya Suzuki, Hajime Ushigome, Hiroki Takahashi, Yoichi Matsuo, Shuji Takiguchi   +9 more
wiley   +1 more source

Nucleosome-mediated cooperativity between transcription factors [PDF]

, 2009
Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes.
Leonid A. Mirny, Mirny, Leonid A
core   +1 more source

Identification and Expression Analysis of Transcription Factor Family in Highland Barley Seedlings Under Na₂SeO₃ Treatment

Life
Transcription factors (TFs) are ubiquitously distributed in plants and play pivotal roles in regulating plant growth and development. The present study aims to elucidate the function of transcription factors (TFs) in highland barley’s response to ...
Xiaozhuo Wu, Feng Qiao, Guigong Geng, Jianxia Ma, Huichun Xie   +4 more
doaj   +1 more source

DNA binding by the plant-specific NAC transcription factors in crystal and solution:a firm link to WRKY and GCM transcription factors

, 2012
NAC (NAM/ATAF/CUC) plant transcription factors regulate essential processes in development, stress responses and nutrient distribution in important crop and model plants (rice, Populus, Arabidopsis), which makes them highly relevant in the context of ...
Welner, Ditte Hededam, Lo Leggio, Leila, Grossmann, J. Günter, Lindemose, Søren, Møllegaard, Niels Erik, Olsen, Addie Nina, Skriver, Karen, Helgstrand, Charlotte   +7 more
core   +1 more source

Comparative in silico analysis of miRNA targeting of NAC and MYB transcription factors associated with secondary cell wall regulation in rice and maize

Frontiers in Plant Science
Cellulose biosynthesis and secondary cell wall formation are regulated by hierarchical networks involving NAC and MYB transcription factors and their post-transcriptional regulation by miRNAs.
Ayaz Belkozhayev, Nargiz Gizatullina, Nargiz Gizatullina, Gaukhargul Yelemessova, Gaukhargul Yelemessova, Madina Mussalimova, Madina Mussalimova, Ronagul Turganova, Ronagul Turganova, Ronagul Turganova, Bekzhan D. Kossalbayev, Bekzhan D. Kossalbayev, Bekzhan D. Kossalbayev, Aizhan Rakhmetullina, Anna Pyrkova, Anna Pyrkova, Anatoliy Ivashchenko, Anatoliy Ivashchenko, Gaukhar Toleutay, Gaukhar Toleutay   +19 more
doaj   +1 more source

GmNAC5, a NAC Transcription Factor, Is a Transient Response Regulator Induced by Abiotic Stress in Soybean

The Scientific World Journal, 2013
GmNAC5 is a member of NAM subfamily belonging to NAC transcription factors in soybean (Glycine max (L.) Merr.). Studies on NAC transcription factors have shown that this family functioned in the regulation of shoot apical meristem (SAM), hormone ...
Hangxia Jin, Guangli Xu, Qingchang Meng, Fang Huang, Deyue Yu   +4 more
doaj   +1 more source

DNA-binding specificity and molecular functions of NAC transcription factors

, 2005
Udgivelsesdato: October 2005The family of NAC (NAM/ATAF1,2/CUC2) transcription factors has been implicated in a wide range of plant processes, but knowledge onthe DNA-binding properties of the family is limited. Using a reiterative selection procedure on
Ernst, Heidi Asschenfeldt, Lo Leggio, Leila, Olsen, Addie Nina, Skriver, Karen   +3 more
core   +1 more source

Anodal Transcranial Direct Current Stimulation Improves Social Behavior Alongside Neuroplastic Changes in a Tsc2+/− Rat Model of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by altered synaptic connectivity and network organization, resulting in profound impairments in social communication and interaction. Transcranial direct current stimulation (tDCS) represents a promising approach to modulate maladaptive plasticity associated with ASD;
Antonia Ramme, Rebecca Winter, Natalia Jarzebska, Fatih Ögel, Marten Julian Richter, Iveta Vojtechova, Christine Winter, Tomas Petrasek, Robert Waltereit, Nadine Bernhardt   +9 more
wiley   +1 more source