Results 1 to 10 of about 14,475 (116)

The effects of sodium benzoate exposure on learning and neurobehavior during the prepubertal period in rats

Türk Biyokimya Dergisi, 2022
Exposure to food additives, especially during the critical development period, has been associated with some behavioral disorders and learning difficulties in childhood.
İlhan İlter, Kumbul Doğuç Duygu, Büyükbayram Halil İbrahim, Aşcı Çelik Dilek, Gurbuz Nilgun, Gultekin Fatih   +5 more
doaj   +1 more source

In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [¹²⁵I]Iodo-ASEM and [¹⁸F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

Molecules, 2020
The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease,
Cornelius K. Donat, Henrik H. Hansen, Hanne D. Hansen, Ronnie C. Mease, Andrew G. Horti, Martin G. Pomper, Elina T. L’Estrade, Matthias M. Herth, Dan Peters, Gitte M. Knudsen, Jens D. Mikkelsen   +10 more
doaj   +1 more source

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

Toxins, 2021
α-conotoxins are 13–19 amino acid toxin peptides that bind various nicotinic acetylcholine receptor (nAChR) subtypes. α-conotoxin Mr1.7c (MrIC) is a 17 amino acid peptide that targets α7 nAChR.
Alican Gulsevin, Roger L. Papke, Clare Stokes, Hue N. T. Tran, Aihua H. Jin, Irina Vetter, Jens Meiler   +6 more
doaj   +1 more source

Cloning of Two Nicotinic Acetylcholine Receptor Genes from Bemisia tabaci (Gennadius)

Turkish Journal of Agriculture: Food Science and Technology, 2020
Nicotinic acetylcholine receptors (nAChRs) mediate fast cholinergic synaptic transmission in the insect nervous system. Neonicotinoid insecticides exhibit insecticidal activities by targeting these receptors.
Gül Satar, Mehmet Rifat Ulusoy, Ke Dong
doaj   +1 more source

Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages

Marine Drugs, 2022
The α7 nicotinic acetylcholine receptor (nAChR) is widely distributed in the central and peripheral nervous systems and is closely related to a variety of nervous system diseases and inflammatory responses.
Yao Tan, Zhaoli Chu, Hongyu Shan, Dongting Zhangsun, Xiaopeng Zhu, Sulan Luo   +5 more
doaj   +1 more source

Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System

Biomolecules, 2020
Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous lipids. However, the data on the biological activity of acylcholines remain very limited.
Mikhail G. Akimov, Denis S. Kudryavtsev, Elena V. Kryukova, Elena V. Fomina-Ageeva, Stanislav S. Zakharov, Natalia M. Gretskaya, Galina N. Zinchenko, Igor V. Serkov, Galina F. Makhaeva, Natalia P. Boltneva, Nadezhda V. Kovaleva, Olga G. Serebryakova, Sofya V. Lushchekina, Victor A. Palikov, Yulia Palikova, Igor A. Dyachenko, Igor E. Kasheverov, Victor I. Tsetlin, Vladimir V. Bezuglov   +18 more
doaj   +1 more source

Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats. [PDF]

PLoS ONE, 2011
The α7 nicotinic acetylcholine receptor (nAChR) is a potential target for the treatment of cognitive deficits in patients with schizophrenia, ADHD and Alzheimer's disease.
Morten S Thomsen, Mona El-Sayed, Jens D Mikkelsen   +2 more
doaj   +1 more source

Nicotinic Acetylcholine Receptors in the Respiratory Tract

Molecules, 2021
Nicotinic acetylcholine receptors (nAChR) are widely distributed in neuronal and non-neuronal tissues, where they play diverse physiological roles. In this review, we highlight the recent findings regarding the role of nAChR in the respiratory tract with
Monika I. Hollenhorst, Gabriela Krasteva-Christ   +1 more
doaj   +1 more source

Activation of α7 nicotinic acetylcholine receptor promotes HIV-1 transcription

Cell Insight, 2022
Alpha7 nicotinic acetylcholine receptor (α7 nAChR), a hub of the cholinergic anti-inflammatory pathway (CAP), is required for the treatment of inflammatory diseases.
Jing Wen, Caiqi Zhao, Jie Chen, Shuting Song, Zhekai Lin, Shitao Xie, Huaxin Qi, Jianhua Wang, Xiao Su   +8 more
doaj   +1 more source

A Novel α4/7-Conotoxin QuIA Selectively Inhibits α3β2 and α6/α3β4 Nicotinic Acetylcholine Receptor Subtypes with High Efficacy

Marine Drugs, 2022
α6β4 nAChR is expressed in the peripheral and central nervous systems and is associated with pain, addiction, and movement disorders. Natural α-conotoxins (α-CTxs) can effectively block different nAChR subtypes with higher efficacy and selectivity ...
Liujun Wang, Xixi Wu, Xiaopeng Zhu, Dongting Zhangsun, Yong Wu, Sulan Luo   +5 more
doaj   +1 more source