Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells [PDF]
, 2016 In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol.
Alkahtan, Reem M. +6 more
core +7 more sources
Acetylcholine receptor subunit expression in Huntington's disease mouse muscle
Biochemistry and Biophysics Reports, 2021 Huntington's disease (HD) causes neurological impairments, as well as muscle dysfunction, including smaller neuromuscular junctions (NMJs). This study assessed the expression levels of the subunits of the nicotinic acetylcholine receptor (nAChR) in ...
Briana Simpson +3 more
doaj +1 more source
Activity of nAChRs containing α9 subunits modulates synapse stabilization via bidirectional signaling programs [PDF]
, 2009 Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic synapse development.
Elgoyhen, Ana Belen +3 more
core +1 more source
Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor
Marine Drugs, 2021 The α4β2 nAChR is implicated in a range of diseases and disorders including nicotine addiction, epilepsy and Parkinson’s and Alzheimer’s diseases. Designing α4β2 nAChR selective inhibitors could help define the role of the α4β2 nAChR in such disease ...
Xiaosa Wu, David J. Craik, Quentin Kaas
doaj +1 more source
Nicotinic α7 acetylcholine receptor-mediated currents are not modulated by the tryptophan metabolite kynurenic acid in adult hippocampal interneurons [PDF]
, 2011 The tryptophan metabolite, kynurenic acid (KYNA), is classically known to be an antagonist of ionotropic glutamate receptors.
Andrew L. Varnell +3 more
core +3 more sources
Molecules, 2019 Nicotinic acetylcholine receptors (nAChRs), serotonin transporters (SERT) and dopamine transporters (DAT) represent targets for the development of novel nicotinic derivatives acting as multiligands associated with different health conditions, such as ...
Juan Pablo González-Gutiérrez +11 more
doaj +1 more source
Data in Brief, 2020 For a long time, traditional purification and extraction methods for the native Torpedo californica nicotinic acetylcholine receptor in lipid-like detergent complex (nAChR-DC) have compromised its purity, functionality and X-ray structural studies ...
Rafael Maldonado-Hernández +2 more
doaj +1 more source
Characterisation of nicotine receptors on human peripheral blood mononuclear cells (PBMC) [PDF]
, 2009 “The original publication is available at www.springerlink.com”. Copyright Springer. DOI: 10.1007/s00011-008-8171-xAim and objective: The aim of the work was to characterise the nAChRs on human PBMC.
Parsons, M. +2 more
core +1 more source
Marine Drugs, 2020 Tobacco smoking has become a prominent health problem faced around the world. The α3β4 nicotinic acetylcholine receptor (nAChR) is strongly associated with nicotine reward and withdrawal symptom.
Xiaodan Li +6 more
doaj +1 more source
Cholesterol modulates acetylcholine receptor diffusion by tuning confinement sojourns and nanocluster stability [PDF]
, 2018 Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine receptor (nAChR) with single-particle ...
Barrantes, Francisco Jose +2 more
core +2 more sources