Results 71 to 80 of about 63,766 (174)

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

Environmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir, Nihal Turkmen Alemdar, Esin Yulug, Ali Kulaber, Elif Ayazoglu Demir, Nadire Sevdenur Erdogan, Ahmet Mentese, Yuksel Aliyazicioglu   +7 more
wiley   +1 more source

Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway

Journal of Neuroinflammation, 2017
Background α7 nicotinic acetylcholine receptors (nAChRs) are widely distributed throughout the central nervous system and are reported to have neuroprotective properties.
Hiral Patel, Jessica McIntire, Sarah Ryan, Anthone Dunah, Ralph Loring   +4 more
doaj   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro

Virology Journal, 2017
Background The aim of this study were to investigate the possible pro-apoptotic mechanisms of the recombinant Newcastle disease virus (NDV) strain rL-RVG, which expresses the rabies virus glycoprotein, in A549 lung adenocarcinoma cells via the regulation
Yulan Yan, Chunxiang Su, Min Hang, Hua Huang, Yinghai Zhao, Xiaomei Shao, Xuefeng Bu   +6 more
doaj   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark, Kevin M. Gray, Nathaniel L. Baker, Brian J. Sherman, Bryan Tolliver, Jessica Burt, Alonzo Steplight, Elizabeth Chapman, Amanda Wagner   +8 more
wiley   +1 more source

On the stability of compact supermassive objects [PDF]

, 2001
Proceeded from the gravitation equations proposed by one of authors it was argued in a previous paper that there can exist supermassive compact configurations of degenerated Fermi-gas without events horizon. In the present paper we consider the stability
Kochetov, A., Verozub, L.
core   +5 more sources

Personalizing smoking cessation pharmacotherapy using neuroaffective reactivity profiles: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims By assessing neuroaffective response to motivationally relevant cues before a quit attempt, we have shown that smokers who attribute greater incentive salience to cigarette‐related cues than non‐cigarette‐related rewards (Sign‐trackers, ST) benefit more from varenicline compared with smokers with the opposite neuroaffective
Francesco Versace, Charles E. Green, Yong Cui, Jason D. Robinson, Menton M. Deweese, Jennifer A. Minnix, George Kypriotakis, Seokhun Kim, Maher Karam‐Hage, Paul M. Cinciripini   +9 more
wiley   +1 more source

A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site [PDF]

, 2004
To study conformational transitions at the muscle nicotinic acetylcholine (ACh) receptor (nAChR), a rhodamine fluorophore was tethered to a Cys side chain introduced at the beta-19' position in the M2 region of the nAChR expressed in Xenopus oocytes ...
Auyeung, Vincent C., Bezanilla, Francisco, Chanda, Baron, Dahan, David S., Dibas, Mohammed I., Dougherty, Dennis A., Lester, Henry A., Petersson, E. James   +7 more
core  

Mining the ESO WFI and INT WFC archives for known Near Earth Asteroids. Mega-Precovery software

, 2013
The ESO/MPG WFI and the INT WFC wide field archives comprising 330,000 images were mined to search for serendipitous encounters of known Near Earth Asteroids (NEAs) and Potentially Hazardous Asteroids (PHAs).
Badea, M., Badescu, T., Birlan, M., Char, F., Comsa, I., Constantinescu, M., Lacatus, D., Opriseanu, C., Paraschiv, A., Popescu, M., Sonka, A., Suciu, O., Tudorica, A., Vaduvescu, O., Vidican, D.   +14 more
core   +3 more sources

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer, Tom P. Freeman, Martine Skumlien, Esther Walton, Thomas Lancaster, Jorien L. Treur, Valentina Lorenzetti, Anna K. M. Blackwell, Chloe Burke, Richie J. Carr, Constantinos Constantinides, Maisie Cox, Sarah Dance, Shadi Daryan, Sorcha Hamilton, Tom Jenkins, Gemma M. J. Taylor   +16 more
wiley   +1 more source