Results 81 to 90 of about 10,119 (138)
Ethology, EarlyView.A field‐recommended concentration of a commercial imidacloprid formulation reduced open arena activity and slowed climbing in the jumping spider Helpis minitabunda. Exposed spiders still detected a looming predator stimulus, but their responses were reduced.
Reshnu Rajan‐Sheela +2 more
wiley +1 more source
, 2021 Alpha 7 nicotinic acetylcholine receptor (α7 nAChR) is critical for the pathogenesis of Escherichia coli (E. coli) K1 meningitis, a severe central nervous system infection of the neonates. However, little is known about how E.
Liqun Liu (316613) +13 more
core +1 more source
Immunology, EarlyView.Activated T‐cells instigate signalling events leading to the activation of transcription factors, which in turn, act on the nucleus to produce cytokines. We postulate that c‐fos is one of these transcription factors which upregulates the choline acetyltransferase gene responsible for synthesising acetylcholine (ACh).
Jarita Lay, Nicholas Manolios
wiley +1 more source
Molecular dynamic simulation on the conformation of mouse muscle type nAChR
, 2010 A mouse muscle type nAChR model ((α1) 2βδγ) was built based on the cryoelectron microscopic structure of intact Torpedo marmorata nAChR and the high resolution crystal structure of nAChR-α1 subunit.
Sun, Shengai +3 more
core +1 more source
Frontiers in Cellular Neuroscience, 2017 Previous studies have demonstrated immunosuppressive and anti-inflammatory effects of nicotine, including in the experimental autoimmune encephalomyelitis (EAE) model in mice of some forms of multiple sclerosis (MS).
Qiang Liu +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li +19 more
wiley +1 more source
α4β2-nAChR CNiFER: DHβE antagonism.
, 2013 A. Competitive blockade of (±)-epibatidine elicited responses on α4β2-nAChR CNiFERs by DHβE. The EC50 values for each curve shifted from 8.9 nM to 42 nM, 130 nM, and 270 nM for 300 nM, 1 µM, 3 µM DHβE respectively. B.
Arnaud Muller (19570) +8 more
core +1 more source
Müller Glia–Vasculature Interactions in the Developing Retina
Glia, Volume 74, Issue 10, October 2026.Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi +6 more
wiley +1 more source
Molecular modelling of vurtoxin interaction with Torpedo nAChR.
, 2014 Vurtoxin active site residues are shown in red. A - Model of vurtoxin spatial structure. C and N indicate C- and N-termini, respectively. B - Model of vurtoxin complex with receptor extracellular domain at the α-γ subunit interface of the T.
Sergey Yu. Filkin (676713) +9 more
core +1 more source
PLoS ONE, 2013 BackgroundThe cholinergic anti-inflammatory pathway is an endogenous mechanism by which the autonomic nervous system attenuates macrophage activation via nicotinic acetylcholine receptors (nAChR).
Andrea Nemethova +4 more
doaj +1 more source