Results 41 to 50 of about 966,339 (212)

NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis. [PDF]

, 2019
The 5' end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap that protects mRNA from degradation and mediates almost all other aspects of gene expression.
Cai, Zongwei, Chen, Xuemei, Ni, Min, Shao, Xiaojian, Xia, Yiji, Zhang, Hailei, Zhang, Shoudong, Zhong, Huan   +7 more
core  

Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells [PDF]

, 2009
The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture.
Bongard, Robert D, Krenz, Gary S., Lindemer, Brian J, Merker, Marilyn P   +3 more
core   +2 more sources

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

Extracellular vesicles circulating in young organisms promote healthy longevity

Journal of Extracellular Vesicles, 2019
Parabiosis experiments in mice demonstrated that a young environment could partially rejuvenate multiple tissues of old organisms. However, the circulating mediators responsible of such effect have been elusive so far.
Francesco Prattichizzo, Angelica Giuliani, Jacopo Sabbatinelli, Emanuela Mensà, Valeria De Nigris, Lucia La Sala, Paola de Candia, Fabiola Olivieri, Antonio Ceriello   +8 more
doaj   +1 more source

Structural modeling of NAD+ binding modes to PARP-1

Вавиловский журнал генетики и селекции, 2017
The nuclear protein poly (ADP-ribose) polymerase-1 (PARP-1) plays an important role in the signaling and repair of DNA. PARP-1 catalyses covalent binding of poly (ADP-ribose) polymers with itself as well as with other acceptor proteins using NAD+ as a ...
N. V. Ivanisenko, D. A. Zhechev, V. A. Ivanisenko   +2 more
doaj   +1 more source

Information and Material Support to Environmental Education in Slovakia in the Times of Crisis

Acta Educationis Generalis, 2023
Introduction: The undergoing globalization brings epidemiological, economical, energetical, and environmental security risks. The current task in the field of improving the quality of the environment is educating students in schools for adaptation to the
Bilčík Alexander, Bilčíková Jana, Lajčin Daniel, Barnová Silvia   +3 more
doaj   +1 more source

Highly efficient 5\u27 capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase [PDF]

, 2018
Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and NADH, using NAD+ and NADH as non-canonical initiating nucleotides for transcription
Basu, Urmimala, Bird, Jeremy G, Ebright, Richard H., Grudzien-Nogalska, Ewa, Kiledjian, Megerditch, Kuster, David, Nickels, Bryce E., Patel, Smita S., Ramachandran, Aparna, Temiakov, Dmitry, Towheed, Atif, Wallace, Douglas C.   +11 more
core   +1 more source

Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon, Hartmut Cuny, Nana Sunn, Ella M. M. A. Martin, Delicia Z. Sheng, Gavin Chapman, Sally L. Dunwoodie   +6 more
wiley   +1 more source

Effects of Nicotinamide Adenine Dinucleotide on Older Patients with Heart Failure

Reviews in Cardiovascular Medicine
Background: Heart failure (HF) is the main cause of death in middle-aged and older people and is characterized by high morbidity, high mortality, a high rehospitalization rate, and many high-risk groups. Nicotinamide adenine dinucleotide (NAD+) is widely
Zuowei Pei, Min Dong, Xuyang Meng, Wei Yao, Ying Guo, Fang Wang   +5 more
doaj   +1 more source

Arhitekture računala za adaptivno digitalno formiranje dijagrama usmjerenosti radarske antene

Vojnotehnički Glasnik, 1990
Kombiniranjem arhitekture sa slike 7 s principom računala upravljanog tokom podataka (data flow) (u literaturi je takva arhitektura poznata kao 'wavefront processor' ili polja valne fronte), dobivaju se dodatna poboljšanja i u smislu povećanja brzine i u
Karlo Nađ
doaj   +1 more source