Results 31 to 40 of about 300,505 (163)

Cytochemical Localization of NAD (P) H Oxidase in the Myoepithelial Cells of Salivary and Other Exocrine Glands [PDF]

, 1995
Cytochemical localization of NAD (P) H oxidase, a hydrogen-peroxide generating enzyme, has been investigated using the cerium method in several mammalian exocrine glands: (a) salivary glands of the rat, Mongolian gerbil, house musk shrew and man, (b ...
Yasuhisa Inoue, Kunio Takano, Miyazaki, Toshihiro, Takano, Kunio, Inoue, Yasuhisa, Toshihiro Miyazaki   +5 more
core   +1 more source

Effects of Aging on Glucose and Lipid Metabolism in Mice

Aging Cell, Volume 24, Issue 4, April 2025.
Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit evidence of upregulated fatty acid and sphingolipid metabolism reactions that regenerate NAD+ from NADH.
Evan C. Lien, Ngoc Vu, Anna M. Westermark, Laura V. Danai, Allison N. Lau, Yetiş Gültekin, Matthew A. Kukurugya, Bryson D. Bennett, Matthew G. Vander Heiden   +8 more
wiley   +1 more source

Optimization of 1H‐MRS methods for large‐volume acquisition of low‐concentration downfield resonances at 3 T and 7 T

Magnetic Resonance in Medicine, Volume 93, Issue 1, Page 18-30, January 2025.
Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson, Mark A. Elliott, Ravi Prakash Reddy Nanga, Sophia Swago, Walter R. Witschey, Ravinder Reddy   +5 more
wiley   +1 more source

Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair‐Deficient 3xTg/POLβ+/− Alzheimer Disease Mouse Model

Journal of Neurochemistry, Volume 169, Issue 1, January 2025.
Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky, Tyler G. Demarest, M. Todd King, Darlene Estrada, Richard L. Veech, Vilhelm A. Bohr   +5 more
wiley   +1 more source

Przegląd stanu badań nad historią kobiet polskich (1945–1989)

, 2021
W opracowaniu traktującym o problematyce kobiecej z okresu obejmującego lata 1945–1989 przytoczono publikacje tyczące się sfery prawa, ekonomii, socjologii, a także pozycje zbiorowe będące wynikiem przeprowadzanych sympozjów oraz konferencji naukowych ...
Granatowska, Justyna
core   +1 more source

Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila

Aging Cell, Volume 23, Issue 4, April 2024.
Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy, Reyhan Westbrook, Austin King, Nick Khosravian, Neeraj Ochaney, Tagide DeCarvalho, Qinchuan Wang, Yuqiong Yu, Qiao Huang, Adam Said, Michael Abadir, Cissy Zhang, Pratik Khare, Jennifer E. Fairman, Anne Le, Ginger L. Milne, Fernando J. Vonhoff, Jeremy D. Walston, Peter M. Abadir   +18 more
wiley   +1 more source

Metabolic control of mitophagy

European Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.
Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann, Frank Madeo, Abhinav Diwan, Junichi Sadoshima, Simon Sedej, Guido Kroemer, Mahmoud Abdellatif   +6 more
wiley   +1 more source

Personalized Porous Gelatin Methacryloyl Sustained‐Release Nicotinamide Protects Against Noise‐Induced Hearing Loss

Advanced Science, Volume 11, Issue 12, March 27, 2024.
NAD+ decreases in cochlear after noise trauma, and nicotinamide supplementation boosts NAD+ and prevents neuroexcitatory in cochlear by round window administration. Personalized porous gelatin methacryloyl (PGMA) achieves long term drug release in cochlear, and nicotinamide encapsulated PGMA enhances mitochondria and synapse function, and protects ...
Baoyi Feng, Tingting Dong, Xinyu Song, Xiaofei Zheng, Chenxi Jin, Zhenzhe Cheng, Yiqing Liu, Wenjie Zhang, Xueling Wang, Yong Tao, Hao Wu   +10 more
wiley   +1 more source

Efeito do peróxinitrito na atividade das oxidoredutases vasculares [PDF]

, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaO sistema vascular encontra-se constituído por diversas enzimas oxidoredutases dependentes de NAD(P)H, que em situações ...
Batschauer, Anna Paula de Borba
core  

sj-docx-2-nad-10.1177_14550725231157503 - Supplemental material for Drug treatment service procurement: A systematic review of models, goals, and outcomes

, 2023
Supplemental material, sj-docx-2-nad-10.1177_14550725231157503 for Drug treatment service procurement: A systematic review of models, goals, and outcomes by Taina Schneider, Kristiina Kuussaari and Petri Virtanen in Nordic Studies on Alcohol and ...
Kristiina Kuussaari (16427358), Taina Schneider (16427355), Petri Virtanen (13177447)   +2 more
core   +1 more source