NAD+ metabolism controls inflammation during senescence
Molecular & Cellular Oncology, 2019 We have recently discovered that nicotinamide adenine dinucleotide metabolism controls the pro-inflammatory senescence-associated secretory phenotype during cellular senescence.
Timothy Nacarelli, Rugang Zhang
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Natural pentafuranosylnucleos(t)ides and their analogs: structure, functions, synthesis, and perspective of medical application [PDF]
Exploration of Drug SciencePentafuranosylnucleos(t)ides represent a class of natural compounds regulating diverse cell functions being preferably components of biopolymers and also participating as cyclic regulatory low-molecular ligands.
Dmitrii Platov +3 more
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The evaluation of possibilities of sustainable tourism and recreation in the Mrtva Tisa area near Čurug7 [PDF]
Glasnik Srpskog Geografskog Društva, 2008 The preserved parts of the nature or areas that are inteded to be protected and well-planned in terms of harmonizing the nature and tourist activities and recreation could become potential eco-tourist attractions.
Nađ Imre
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The ferroelectric Mott-Hubbard phase of organic (TMTTF)2X conductors
, 2000 We present experimental evidences for a ferro-electric transition in the family of quasi one- dimensional conductors (TMTTF)2X. We interpret this new transition in the frame of the combined Mott-Hubbard state taking into account the double action of the ...
C. Coulon +19 more
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Fragment-based discovery of a regulatory site in thioredoxin glutathione reductase acting as "doorstop" for NADPH entry [PDF]
, 2018 Members of the FAD/NAD-linked reductase family are recognized as crucial targets in drug development for cancers, inflammatory disorders, and infectious diseases.
Angelucci, Francesco +16 more
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Bulletin of Chemical Reaction Engineering & Catalysis, 2019 In this study, a system of photocatalysis for NAD+ regeneration of enzymatic catalysis was constructed. The optimal conditions for the coupling reaction of photocatalysis and biocatalysis were explored.
Shujin Pu +9 more
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Development of the Cerebrospinal Fluid in Early Stage after Hemorrhage in the Central Nervous System
Life, 2021 Extravasation of blood in the central nervous system (CNS) represents a very strong damaged associated molecular patterns (DAMP) which is followed by rapid inflammation and can participate in worse outcome of patients.
Petr Kelbich +10 more
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CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1 [PDF]
, 2018 Macroautophagy/autophagy is an important intracellular mechanism for the maintenance of cellular homeostasis. Here we show that the CERKL (ceramide kinase like) gene, a retinal degeneration (RD) pathogenic gene, plays a critical role in regulating ...
Danna Jia +21 more
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Grabbing the genome by the NADs [PDF]
Chromosoma, 2015 The regions of the genome that interact frequently with the nucleolus have been termed nucleolar-associated domains (NADs). Deep sequencing and DNA-fluorescence in situ hybridization (FISH) experiments have revealed that these domains are enriched for repetitive elements, regions of the inactive X chromosome (Xi), and several RNA polymerase III ...
Matheson, Timothy D., Kaufman, Paul D.
openaire +3 more sources
Cold exposure reinstates NAD+ levels and attenuates hepatocellular carcinoma
Cell StressCold exposure has been historically used for medicinal purposes, but its benefits and associated mechanisms in mammalian organisms still remain unclear.
Tatiana P Grazioso +4 more
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