Results 11 to 20 of about 213,525 (212)
CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice [PDF]
Background CycloZ, a combination of cyclo-His-Pro and zinc, has anti-diabetic activity. However, its exact mode of action remains to be elucidated.
Jongsu Jeon +15 more
doaj +1 more source
Conceptual framework for SARS-CoV-2–related lymphopenia
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Ilnaz Rahimmanesh +3 more
doaj +1 more source
Textile pattern design is a challenging task that can be hardly resolved by a single deep neural network, due to the requirements on high resolution, periodic tiling, copyright protection and aesthetic preference of designers. In this paper, we present our NAD system which can automatically produce high-quality textile patterns for printing industry ...
Zhifei Pang +4 more
openaire +2 more sources
Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages
Immunosenescence encompasses multiple age-related adaptations that result in increased susceptibility to infections, chronic inflammatory disorders, and higher mortality risk.
Rafael Moura Maurmann +3 more
doaj +1 more source
Enfermedad del coronavirus (covid-19) y las sirtuinas
Las proteínas desacetilasas dependientes del NAD+, se denominan Sirtuinas (SIRT). Objetivos: estudiar las sirtuinas involucradas en el cáncer, así como los estudios de inhibición de SIRT1 en pacientes con la enfermedad del coronavirus COVID-19 ...
Ronald Eleazar Huarachi Olivera +1 more
doaj +1 more source
CD38 in Neurodegeneration and Neuroinflammation
Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro +3 more
doaj +1 more source
Tuberculosis is an infectious disease, which is caused by the Mycobacterium tuberculosis complex. This disease leads to up to 1.3 million deaths out of more than eight million cases every year.
Selami Gunal +2 more
doaj +1 more source
Nicotinamide riboside (NR) and caffeine increase nicotinamide adenine dinucleotide (NAD), transiently modulate bioenergetic functions, and change the expression of NAD‐synthesizing, recycling, or degrading genes in dermal fibroblasts or induced pluripotent stem cell (iPSC)‐derived neural progenitors and astrocytes from late‐onset Alzheimer's disease ...
Woo‐In Ryu +6 more
wiley +1 more source
CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis
CD38 is a membrane‐bound protein. This study primarily implicates CD38 as an important regulator of chondrogenic differentiation. Inhibition of CD38 demonstrated protection against cartilage degeneration, which suggests that CD38 could be a potential therapeutic target for OA.
Jin‐jin Ma +9 more
wiley +1 more source
Investigation of sand in piping [PDF]
For the investigation of the grain size distribution of the material washed out from the piping, we used 20 samples originating from different places on the Danube and the Tisza rivers.
Nađ Laslo
doaj +1 more source

