Results 41 to 50 of about 299,285 (291)

Structural characterization of borneol dehydrogenase from Pseudomonas sp. TCU‐HL1

open access: yesActa Crystallographica Section F, Volume 76, Issue 7, Page 309-313, July 2020., 2020
The structure of a Pseudomonas borneol dehydrogenase was determined at 1.84 Å resolution. Major differences from its homologues in the C‐terminal helices and the associated loops may suggest determinants for substrate recognition.During the microbial degradation of borneol, a bicyclic plant monoterpene, it is first converted into camphor by borneol ...
Aye Aye Khine   +3 more
wiley   +1 more source

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

open access: yesNature Communications, 2018
Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calorie restriction on healthspan.
C. Martens   +7 more
semanticscholar   +1 more source

NAD+ Metabolism in Cardiac Health, Aging, and Disease.

open access: yesCirculation, 2021
Nicotinamide adenine dinucleotide (NAD+) is a central metabolite involved in energy and redox homeostasis as well as in DNA repair and protein deacetylation reactions.
M. Abdellatif, S. Sedej, G. Kroemer
semanticscholar   +1 more source

Evolutionary Views of Tuberculosis: Indoleamine 2,3‐Dioxygenase Catalyzed Nicotinamide Synthesis Reflects Shifts in Macrophage Metabolism

open access: yesBioEssays, Volume 42, Issue 5, May 2020., 2020
Classically activated macrophages upregulate Warburg‐like metabolism while alternatively activated M2 macrophages utilize the Krebs cycle and oxidative phosphorylation. M2 macrophages upregulate indoleamine 2,3‐dioxygenase for de novo nicotinamide adenine dinucleotide (NAD) synthesis.
Melinda S. Suchard   +3 more
wiley   +1 more source

A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure [PDF]

open access: yesStructure, 1998
Nicotinamide adenine dinucleotide (NAD+) has a central role in life processes. The ubiquitous enzyme NAD+ synthetase catalyzes a key step in NAD+ biosynthesis, transforming deamido-NAD+ into NAD+ by a two-step reaction. NAD+ synthetase belongs to the amidotransferase family and has been recognized as a member of the family of N-type ATP ...
RIZZI, Menico, BOLOGNESI M., CODA A.
openaire   +3 more sources

Outlook of logging perspectives in the Czech Republic for the period 2013-2032

open access: yesJournal of Forest Science, 2014
The aim of the submitted work was to analyze the outlook of logging perspectives in the next two decades (2013-2032) for all forests in the territory of the Czech Republic.
M. Synek, J. Vašíček, M. Zeman
doaj   +1 more source

CD38 ecto-enzyme in immune cells is induced during aging regulating NAD+ and NMN levels

open access: yesNature Metabolism, 2020
Decreased NAD+ levels have been shown to contribute to metabolic dysfunction during aging. NAD+ decline can be partially prevented by knockout of the enzyme CD38.
Claudia C S Chini   +31 more
semanticscholar   +1 more source

Psychomotor activities in the context of kinanthropology: Review

open access: yesTělesná Kultura, 2015
BACKGROUND: Any scholar developing a therapeutic method shall be concerned with its historical and theoretical groundings, scientifically verifiedfacts, and information from professional publications.
Běla Hátlová   +2 more
doaj   +1 more source

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice

open access: yesScience, 2016
A dietary supplement protects aging muscle The oxidized form of cellular nicotinamide adenine dinucleotide (NAD+) is critical for mitochondrial function, and its supplementation can lead to increased longevity. Zhang et al.
Hongbo Zhang   +12 more
semanticscholar   +1 more source

Threat of Pollution Hotspots Reworking in River Systems: Case Study of the Ploučnice River (Czech Republic)

open access: yesISPRS International Journal of Geo-Information, 2019
As fluvial pollution may endanger the quality of water and solids transported by rivers, mapping and evaluation of historically polluted fluvial sediments is an urgent topic.
Jitka Elznicová   +5 more
doaj   +1 more source

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