Results 41 to 50 of about 1,064,600 (267)

Targeted and untargeted metabolomics provide insight into the consequences of glycine‐N‐methyltransferase deficiency including the novel finding of defective immune function

open access: yesPhysiological Reports, Volume 8, Issue 18, September 2020., 2020
Abstract Fatty liver disease is increasing along with the prevalence of obesity and type‐2 diabetes. Hepatic fibrosis is a major health complication for which there are no efficacious treatment options available. A better understanding of the fundamental mechanisms that contribute to the accumulation of fibrosis is needed.
Brandon J. Eudy   +3 more
wiley   +1 more source

Structural dynamic modification of circular disc using pre-stressed fields

open access: yesResearch in Agricultural Engineering, 2005
Dynamical properties of circular discs are investigated in this paper. One of the techniques of the disc modifications to achieve the required dynamic properties is to initiate pre-stress in disc plane.
M. Naď
doaj   +1 more source

Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells [PDF]

open access: yes, 2009
The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture.
Bongard, Robert D   +3 more
core   +2 more sources

Structural characterization of borneol dehydrogenase from Pseudomonas sp. TCU‐HL1

open access: yesActa Crystallographica Section F, Volume 76, Issue 7, Page 309-313, July 2020., 2020
The structure of a Pseudomonas borneol dehydrogenase was determined at 1.84 Å resolution. Major differences from its homologues in the C‐terminal helices and the associated loops may suggest determinants for substrate recognition.During the microbial degradation of borneol, a bicyclic plant monoterpene, it is first converted into camphor by borneol ...
Aye Aye Khine   +3 more
wiley   +1 more source

Evaluation of NAD(+)-dependent DNA ligase of mycobacteria as a potential target for antibiotics [PDF]

open access: yes, 2007
Mycobacteria contain genes for several DNA ligases, including ligA, which encodes a NAD+-dependent enzyme that has been postulated to be a target for novel antibacterial compounds.
Bowater, Richard P.   +6 more
core   +2 more sources

NAD+ Metabolism in Cardiac Health, Aging, and Disease.

open access: yesCirculation, 2021
Nicotinamide adenine dinucleotide (NAD+) is a central metabolite involved in energy and redox homeostasis as well as in DNA repair and protein deacetylation reactions.
M. Abdellatif, S. Sedej, G. Kroemer
semanticscholar   +1 more source

The ferroelectric Mott-Hubbard phase of organic (TMTTF)2X conductors

open access: yes, 2000
We present experimental evidences for a ferro-electric transition in the family of quasi one- dimensional conductors (TMTTF)2X. We interpret this new transition in the frame of the combined Mott-Hubbard state taking into account the double action of the ...
C. Coulon   +19 more
core   +2 more sources

Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

open access: yesNature Metabolism
Mitochondrial dysfunction and low nicotinamide adenine dinucleotide (NAD+) levels are hallmarks of skeletal muscle ageing and sarcopenia1–3, but it is unclear whether these defects result from local changes or can be mediated by systemic or dietary cues.
Mathieu Membrez   +34 more
semanticscholar   +1 more source

Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases [PDF]

open access: yes, 2003
Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD(+), divalent metal cations, and reducing conditions. The family is also unique in its inclusion of both alpha- and beta-specific enzymes.
Hoffmann, Volker   +4 more
core   +2 more sources

Sava Savanović: el primer vampiro serbio y los muertos vivientes de los Balcanes

open access: yesBalajú, 2016
Este artículo se presenta una breve exposición de las tradiciones culturales en torno a los vampiros en las zonas de Serbia, Ucrania y la Transilvania medieval.
Jelena Nađ
doaj   +1 more source

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