Results 61 to 70 of about 205,573 (216)
Pathway analysis of NAD+ metabolism [PDF]
Biochemical Journal, 2011 NAD+ is well known as a crucial cofactor in the redox balance of metabolism. Moreover, NAD+ is degraded in ADP-ribosyl transfer reactions, which are important components of multitudinous signalling reactions. These include reactions linked to DNA repair and aging.
Toni I. Gossmann +5 more
openaire +4 more sources
Structural dynamic modification of vibrating systems [PDF]
Applied and Computational Mechanics, 2007 Vibration and acoustic requirements are becoming increasingly important in the design of mechanical structures. The need to vary the structural behaviour to solve noise and vibration problems occurs at design or prototype stage, giving rise to the so ...
Naď M.
doaj
Journal of Neurochemistry, Volume 169, Issue 1, January 2025.Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky +5 more
wiley +1 more source
NAD+ Homeostasis and NAD+-Consuming Enzymes: Implications for Vascular Health
Antioxidants, 2023 Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been attracting markedly increasing interest since they have been demonstrated to be involved in several crucial biological pathways, impacting genes transcription, cellular signaling, and ...
Roberto Campagna, Arianna Vignini
openaire +3 more sources
AMERICAN MULTI-DWELLING ARCHITECTURE OF THE SECOND HALF OF THE 19TH CENTURY AND FIRST HALF OF THE 20TH CENTURY [PDF]
AR: Arhitektura, Raziskave, 2013 At the end of the 19th and beginning of the 20th century, the evolution of American multiple-dwelling architecture was marked by the passage from the standard construction of single-family standalone homes and row houses to a new housing typology which ...
Srđan Nađ
doaj
Aging Cell, Volume 23, Issue 4, April 2024.Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy +18 more
wiley +1 more source
Can Aspartate Aminotransferase in the Cerebrospinal Fluid Be a Reliable Predictive Parameter?
Brain Sciences, 2020 Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities of aspartate aminotransferase (AST) in the cerebrospinal fluid (CSF) to detect brain ischemia were determined in this ...
Petr Kelbich +9 more
doaj +1 more source
Corporate Social Responsibility of Organizations as Part of a Quality Management System
Production Engineering Archives, 2021 The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena +2 more
doaj +1 more source
Metabolic control of mitophagy
European Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann +6 more
wiley +1 more source
ISPRS International Journal of Geo-Information, 2019 As fluvial pollution may endanger the quality of water and solids transported by rivers, mapping and evaluation of historically polluted fluvial sediments is an urgent topic.
Jitka Elznicová +5 more
doaj +1 more source