Results 61 to 70 of about 1,064,600 (267)

Intestinal Fut2 deficiency exacerbated alcohol‐related liver disease by disrupting nicotinamide metabolism

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Loss of intestinal epithelial fucosylation exacerbates alcohol‐related liver injuries. Intestinal epithelial deletion of Fut2 disrupts nicotinamide (NAM) metabolism due to the decline in bacterial nicotinamidase (PncA). Supplemented with pncA overexpressed E.coli to restore gut PncA levels can improve liver damage in alcohol‐induced intestinal ...
Liuying Chen, Zhongwei Yin, Luorui Shang, Hang Yuan, Wenkang Gao, Shuhan Wang, Shuyan Wang, Xiaohua Hou, Shenglan Yang, Huikuan Chu   +9 more
wiley   +1 more source

Psychomotor activities in the context of kinanthropology: Review

Tělesná Kultura, 2015
BACKGROUND: Any scholar developing a therapeutic method shall be concerned with its historical and theoretical groundings, scientifically verifiedfacts, and information from professional publications.
Běla Hátlová, Iva Wedlichová, Milena Adámková Ségard   +2 more
doaj   +1 more source

Stopping the Mobile Robotic Vehicle at a Defined Distance from the Obstacle by Means of an Infrared Distance Sensor

Sensors, 2021
The article deals with the creation of a program for stopping an autonomous robotic vehicle Robotino® 4. generation at a defined distance from an obstacle. One of the nine infrared distance sensors located on the frame of the robotic vehicle in the front
Frantisek Klimenda, Roman Cizek, Matej Pisarik, Jan Sterba   +3 more
doaj   +1 more source

Highly efficient 5\u27 capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase [PDF]

, 2018
Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD+ and NADH, using NAD+ and NADH as non-canonical initiating nucleotides for transcription
Basu, Urmimala, Bird, Jeremy G, Ebright, Richard H., Grudzien-Nogalska, Ewa, Kiledjian, Megerditch, Kuster, David, Nickels, Bryce E., Patel, Smita S., Ramachandran, Aparna, Temiakov, Dmitry, Towheed, Atif, Wallace, Douglas C.   +11 more
core   +1 more source

Maternal Circulatory NAD Precursor Levels and the Yolk Sac Determine NAD Deficiency‐Driven Congenital Malformation Risk

The FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Maternal circulatory L‐tryptophan (TRP) and nicotinamide (NAM) levels are proportional to dietary TRP intake. Yolk sacs, but not embryos, perform NAD de novo synthesis. This study explores the exchange of NAD precursors between mother and conceptus, and NAD generation in conceptal tissues via the NAD de novo synthesis (blue) or salvage (red) pathways ...
Kayleigh Bozon, Hartmut Cuny, Delicia Z. Sheng, Alena Sipka, Antonia W. Shand, Natasha Nassar, Sally L. Dunwoodie   +6 more
wiley   +1 more source

Effects of Aging on Glucose and Lipid Metabolism in Mice

Aging Cell, Volume 24, Issue 4, April 2025.
Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit evidence of upregulated fatty acid and sphingolipid metabolism reactions that regenerate NAD+ from NADH.
Evan C. Lien, Ngoc Vu, Anna M. Westermark, Laura V. Danai, Allison N. Lau, Yetiş Gültekin, Matthew A. Kukurugya, Bryson D. Bennett, Matthew G. Vander Heiden   +8 more
wiley   +1 more source

Structural dynamic modification of vibrating systems [PDF]

Applied and Computational Mechanics, 2007
Vibration and acoustic requirements are becoming increasingly important in the design of mechanical structures. The need to vary the structural behaviour to solve noise and vibration problems occurs at design or prototype stage, giving rise to the so ...
Naď M.
doaj  

Identifying and categorizing influencers on Instagram with eye tracker [PDF]

Spanish Journal of Marketing-ESIC
Purpose – This paper aims to explore the recognition and success of different ways of branding native advertising in influencer marketing. Design/methodology/approach – The data are evaluated using statistical tests, correlation and cluster analysis ...
Michaela Jánská, Marta Žambochová, Zuzana Vacurová   +2 more
doaj   +1 more source

Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone [PDF]

, 2000
We have applied the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens to a cell-free system for the regeneration of the nicotinamide cofactors NAD and NADP in the biological production of the important semisynthetic opiate drug ...
Boonstra, B, Bruce, N C, French, C E, Rathbone, D A, Walker, E H   +4 more
core   +2 more sources

Optimization of 1H‐MRS methods for large‐volume acquisition of low‐concentration downfield resonances at 3 T and 7 T

Magnetic Resonance in Medicine, Volume 93, Issue 1, Page 18-30, January 2025.
Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson, Mark A. Elliott, Ravi Prakash Reddy Nanga, Sophia Swago, Walter R. Witschey, Ravinder Reddy   +5 more
wiley   +1 more source