Results 61 to 70 of about 761,247 (215)
Magnetic Resonance in Medicine, Volume 93, Issue 1, Page 18-30, January 2025.Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson +5 more
wiley +1 more source
Corporate Social Responsibility of Organizations as Part of a Quality Management System
Production Engineering Archives, 2021 The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena +2 more
doaj +1 more source
Pathway analysis of NAD+ metabolism [PDF]
Biochemical Journal, 2011 NAD+ is well known as a crucial cofactor in the redox balance of metabolism. Moreover, NAD+ is degraded in ADP-ribosyl transfer reactions, which are important components of multitudinous signalling reactions. These include reactions linked to DNA repair and aging.
Toni I. Gossmann +5 more
openaire +4 more sources
Journal of Neurochemistry, Volume 169, Issue 1, January 2025.Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky +5 more
wiley +1 more source
FEBS Open Bio, Volume 7, Issue 12, Page 1830-1842, December 2017., 2017 Multifunctional enzyme, type‐1 (MFE1) is a monomeric enzyme, with a 2E‐enoyl‐CoA hydratase (blue, green) and a 3S‐hydroxyacyl‐CoA dehydrogenase (HAD, orange, red, yellow) active site. The mode of binding of acetoacetyl‐CoA (hydratase part) and NAD+ (HAD part), shown as ball‐and‐stick models, is described.
Prasad Kasaragod +6 more
wiley +1 more source
NAD tagSeq reveals that NAD+-capped RNAs are mostly produced from a large number of protein-coding genes in Arabidopsis. [PDF]
, 2019 The 5' end of a eukaryotic mRNA transcript generally has a 7-methylguanosine (m7G) cap that protects mRNA from degradation and mediates almost all other aspects of gene expression.
Cai, Zongwei +7 more
core
Evaluation of NAD(+)-dependent DNA ligase of mycobacteria as a potential target for antibiotics [PDF]
, 2007 Mycobacteria contain genes for several DNA ligases, including ligA, which encodes a NAD+-dependent enzyme that has been postulated to be a target for novel antibacterial compounds.
Bowater, Richard P. +6 more
core +2 more sources
Aging Cell, Volume 23, Issue 4, April 2024.Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy +18 more
wiley +1 more source
Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra [PDF]
, 2007 Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement of whole blood NAD and NADP concentrations. To compare these methods,
Cheung, E +5 more
core +2 more sources
Biology, 2020 Use of plant growth-promoting bacteria (PGPB) for cultivation of the biofuel crop Miscanthus × giganteus (Mxg) in post-military and post-mining sites is a promising approach for the bioremediation of soils contaminated by metals.
Kumar Pranaw +3 more
doaj +1 more source