Measurement of Chloroplastic NAD Kinase Activity and Whole Tissue NAD Kinase Assay [PDF]
Bio-Protocol, 2020 Nicotinamide adenine dinucleotide phosphate (NADP) synthesis requires nicotinamide adenine dinucleotide (NAD) kinase activity, substrate NAD and ATP.
Yuma Ishikawa +2 more
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Mitochondrial NAD kinase in health and disease [PDF]
Redox Biology, 2023 Nicotinamide adenine dinucleotide phosphate (NADP), a co-enzyme and an electron carrier, plays crucial roles in numerous biological functions, including cellular metabolism and antioxidation.
Ren Zhang, Kezhong Zhang
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New Chemical Probe Targeting Bacterial NAD Kinase [PDF]
Molecules, 2020 Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic pathways.
David A. Clément +8 more
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Molecular properties and regulation of NAD+ kinase (NADK) [PDF]
Redox Biology, 2023 Nicotinamide adenine dinucleotide (NAD+) kinase (NADK) phosphorylates NAD+, thereby producing nicotinamide adenine dinucleotide phosphate (NADP). Both NADK genes and the NADP(H)-producing mechanism are evolutionarily conserved among archaea, bacteria ...
Shin-ichi Oka +3 more
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Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis [PDF]
mBio, 2023 Nicotinamide adenine dinucleotide (NAD) and its phosphorylated derivative (NADP) are essential cofactors that participate in hundreds of biochemical reactions and have emerged as therapeutic targets in cancer, metabolic disorders, neurodegenerative ...
Ritu Sharma +11 more
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Physiological Significance of NAD Kinases in Cyanobacteria
Frontiers in Plant Science, 2019 Unicellular cyanobacteria are thought to be the evolutionary ancestors of plant chloroplasts and are widely used both for chemical production and as model organisms in studies of photosynthesis. Although most research focused on increasing reducing power
Yuuma Ishikawa, Maki Kawai-Yamada
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Nicotinamide riboside kinase structures reveal new pathways to NAD+.
PLoS Biology, 2007 The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and ...
Wolfram Tempel +10 more
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Regulation of redox homeostasis and proline metabolism by tea polyphenols ameliorates salinity tolerance during wheat seed germination and early seedling growth [PDF]
BMC Plant BiologySalt stress constitutes a significant abiotic constraint impairing seed germination and plant growth. In this study, we employed wheat cultivar 'Longchun 30' to examine tea polyphenol (TP)-mediated regulation of redox homeostasis and proline metabolism ...
Hui Ma +5 more
doaj +2 more sources
Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells [PDF]
Nature CommunicationsT cell metabolism increases upon activation, underpinning immune effector functions. Nicotinamide adenine dinucleotide (NAD/H) is an essential redox cofactor for glycolysis and mitochondrial substrate oxidation.
Victoria Stavrou +21 more
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Metabolic changes associated with dark-induced leaf senescence in Arabidopsis nadk2 mutants
Plant Signaling & Behavior, 2023 Arabidopsis NADK2 (NAD kinase 2) is a chloroplast-localized enzyme involved in NADP+ synthesis, which acts as the final electron acceptor in the photosynthetic electron transfer chain.
chaomurilege +5 more
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