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Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics
, 2009 We have examined sequence diversity of 147 co-crystal structures of proteins utilizing NAD as a cofactor or as a substrate. Most of these proteins bind NAD in an extended conformations. However, there are clear exceptions to this general trend. Several bacterial reductases bind NAD in an extremely folded conformations.
Riccardo Petrelli +9 more
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, 2011 NAD kinase (NADK) is a key enzyme that regulates supply of NADP in the cell. At this time no other pathway of NADP biosynthesis has been found in prokaryotic or eukaryotic cells. Human NAD kinase catalyzes a magnesium- dependent phosphorylation of the 2’-hydroxyl group of the adenosine ribose moiety of NAD using ATP as phosphoryl donor to give NADP ...
Loredana Cappellacci +9 more
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Men and women differ in large part resulting from the presence or absence of gynecologic organs including the ovaries, the uterus, the lining of which is known as the endometrium, and the entry to the uterus (womb), the cervix (1), all of which are targets for development of malignancies (2-7); vulvar cancer is less common (8).
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The Relationship Between Chilling Injury and NADK Activity in Postharvest Banana Fruits
, 2008 Caiqin Gu
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