Advanced Biomedical Research, 2017 Background:Staphylococcus aureus has the ability to form biofilms on any niches, a key pathogenic factor of this organism and this phenomenon is directly related to the concentration of NADPH.
U Venkateswara Prasad +7 more
doaj +2 more sources
The role of respiration metabolism in dicyclohexylcarbodiimide and disodium succinate regulating the pulp breakdown occurrence of fresh longan (Dimocarpus longan Lour.) during storage [PDF]
Food Chemistry: XCompared to control longan, on day 6, DCC-treated longan presented 18 %, 2 %, 15 %, 34 %, 21 %, 26 % and 10 % higher levels of pulp breakdown index, fruit respiration rate, PGI, SDH, NAD, NADH and QH2, respectively.
Yi Zheng +9 more
doaj +2 more sources
Serum proteome profiling of plateau acclimatization in men using Olink proteomics approach [PDF]
Physiological ReportsPlateau acclimatization involves adaptive changes in the body's neurohumoral regulation and metabolic processes due to hypoxic conditions at high altitudes.
Jingyu Pan +7 more
doaj +2 more sources
Alpha-ketoglutarate accelerates granulocyte-monocyte progenitor differentiation and atherosclerotic plaque inflammation via oxoglutarate receptor 1 [PDF]
Redox BiologyAccumulating evidence shows that excess cholesterol and glucose uptake stimulates the expansion of hematopoietic stem/progenitor cells and myeloid progenitors, resulting in increased production of inflammatory cells and atherosclerotic progression ...
Jiwei Zhao +10 more
doaj +2 more sources
Construyendo el metabolismo del NAD(P)+ en Plasmodium falciparum: estudio de la NADK y la NMNAT [PDF]
, 2018 La Nicotinamida/Nicotinato monucleótido adenililtransferasa (NMNAT) y la Quinasa del Dinucleótido de adenina y Nicotinamida (NADK) son dos enzimas centrales en el metabolismo del NAD+, la primera de ellas esencial para su síntesis y la segunda para su fosforilación generando NADP+. En el parásito protozoo P.
Guasca Pineda, Laura Katherine
openaire +2 more sources
NMN partially rescues cuproptosis by upregulating sirt2 to increase intracellular NADPH [PDF]
Scientific ReportsCuproptosis is characterized by lipoylated protein aggregation and loss of iron–sulfur (Fe–S) proteins, which are crucial for a wide range of important cellular functions, including DNA replication and damage repair. Sirt2 and sirt4 are lipoamidases that
Yingying Zhang +9 more
doaj +2 more sources
, 2011 NAD kinase (NADK) is a key enzyme that regulates supply of NADP in the cell. At this time no other pathway of NADP biosynthesis has been found in prokaryotic or eukaryotic cells. Human NAD kinase catalyzes a magnesium- dependent phosphorylation of the 2’-hydroxyl group of the adenosine ribose moiety of NAD using ATP as phosphoryl donor to give NADP ...
CAPPELLACCI, Loredana +9 more
core +3 more sources
Neuronal or Intestinal Knockdown of C. elegans nadk-1 Decreases Oxygen Consumption and Reactive Oxygen Species [PDF]
, 2023 Reactive oxygen species (ROS) such as H2O2 can damage cellular components and are formed as a byproduct of mitochondrial oxidative metabolism. Studies using the nematode C.
Regan, Jake
core +3 more sources
A Novel Polyphosphate-Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii. [PDF]
Environ MicrobiolA novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Nicholls JWF +4 more
europepmc +2 more sources
Cryo-EM structure and regulation of human NAD kinase. [PDF]
Sci AdvInternational audienceReduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial reducing cofactor for reductive biosynthesis and protection from oxidative stress.
Praharaj PP +18 more
europepmc +5 more sources