Results 41 to 50 of about 1,174 (166)
Background NAD kinases (NADKs) are the only known enzymes that directly phosphorylate NAD(H) to generate NADP(H) in different subcellular compartments. They participate in multiple life activities, such as modulating the NADP/NAD ratio, maintaining the ...
Xiang Wang +8 more
doaj +1 more source
Reactive oxygen species (ROS) such as H2O2 can damage cellular components and are formed as a byproduct of mitochondrial oxidative metabolism. Studies using the nematode C.
Regan, Jake
core +1 more source
Nearly all multicellular organisms show changes in redox balance with aging leading to oxidative damage of macromolecules. This study investigated the role of the [NADP+]/[NADPH] redox couple in aging.
Gong, Henry
core
International audienceNicotinamide adenine dinucleotide kinases (NAD kinases) are essential and ubiquitous enzymes involved in the production of NADP(H) which is an essential cofactor in many metabolic pathways.
Mondange, Lou +9 more
core +1 more source
Beta (β)-carotene (C40H56; a provitamin) is a particularly important carotenoid for human health. Many studies have focused on engineering Escherichia coli as an efficient heterologous producer of β-carotene.
Yuanqing Wu +14 more
doaj +1 more source
Choanoflagellates, euglenozoans, and the cnidarian Stylophora pistillata eukaryotic mito-clade NADK genes while also possessing nadk genes apparently acquired from different lineages of α-proteobacteria. These apparent cases of HGT thus appear to be “α2m”
Albert Erives (269738) +1 more
core +1 more source
Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva +5 more
wiley +1 more source
Many eukaryotic protists do not possess the mito-clade NADK gene of plants and animals.
Unlike fungi, amoebozoans, and chlorophytes, all of which have additional NADK cyto-clade genes while missing a mito-clade NADK gene, many eukaryotic protist lineages that are also missing mito-clade NADK genes possess NADK cyto-clade genes that are only
Albert Erives (269738) +1 more
core +1 more source
Background: Multiple myeloma (MM) is characterized by malignant proliferation of plasma cells (PC) which accumulate in the bone marrow (BM). The advent of new drugs has changed the course of the disease from incurable to treatable, but most patients ...
Sabina Sevcikova +7 more
doaj +1 more source
ABSTRACT Objective With the burden of diabetes rising in Australia, it is important to understand the challenges for rurally based health practitioners to achieve credentialling as a diabetes educator. Setting This is particularly relevant in rural and remote Australia with the shortage of credentialled diabetes educators and the great burden of ...
Arjun Chhabra +3 more
wiley +1 more source

