Results 91 to 100 of about 72,905 (323)

Identification of the NADP+ Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from Giardia lamblia

open access: yesBiomolecules, 2019
Giardia lambia is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that G. lamblia exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate ...
Laura Morales-Luna   +17 more
doaj   +1 more source

Bisphenol A Induces Neuronal Apoptosis and Oxidative Stress Through TRPV4 Channel Signaling Pathways: Protective Role of Alpha‐Lipoic Acid

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), an environmental toxin, exerts adverse effects by increasing mitochondrial (mROS) and intracellular (iROS) reactive oxygen species, apoptosis, and Ca2+ influx in neurological diseases. However, antioxidants can mitigate these detrimental effects. This study aimed to investigate the protective role of antioxidant alpha‐lipoic
Ramazan Çinar, Mustafa Nazıroğlu
wiley   +1 more source

Antisense Reduction of NADP-Malic Enzyme in Flaveria bidentis Reduces Flow of CO2 through the C4 Cycle[W][OA]

open access: yesPlant Physiology, 2012
An antisense construct targeting the C4 isoform of NADP-malic enzyme (ME), the primary enzyme decarboxylating malate in bundle sheath cells to supply CO2 to Rubisco, was used to transform the dicot Flaveria bidentis.
Jasper J. L. Pengelly   +3 more
semanticscholar   +1 more source

Initial ATP Formation, NADP Reduction, CO2 Fixation, and Chloroplast Flattening Upon Illuminating Pea Leaves [PDF]

open access: bronze, 1969
Park S. Nobel   +4 more
openalex   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

Aluminium effects on pyridine nucleotide redox state in roots of Scots pine

open access: yesActa Societatis Botanicorum Poloniae, 2014
After prolonged (3-9 weeks) hydroponic treatment of Scots pine seedlings with different concentrations (0.5-4.0 mM) of Al (AI(N03)3), the levels of pyridine nucleotides were determined in root homogenates.
Gabriela Lorenc-Plucińska   +1 more
doaj   +1 more source

Glutaminase‐1 Mediated Glutaminolysis to Glutathione Synthesis Maintains Redox Homeostasis and Modulates Ferroptosis Sensitivity in Cancer Cells

open access: yesCell Proliferation, EarlyView.
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai   +13 more
wiley   +1 more source

Sources of reducing equivalents for nitrite reductase in Pisum arvense roots

open access: yesActa Societatis Botanicorum Poloniae, 2014
Glucose-6-phosphate and NADP+ as well as malic acid and NADP+ present in the incubation mixture enhanced nitrite reductase (EC 1.6.6.4) activity in Pisum arvense roots.
Grażyna Kłobus
doaj   +1 more source

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