Results 91 to 100 of about 141,947 (341)

NAD(P)H Drives the Ascorbate–Glutathione Cycle and Abundance of Catalase in Developing Beech Seeds Differently in Embryonic Axes and Cotyledons

Antioxidants, 2021
European beech is an important component of European lowland forests in terms of ecology, and produces irregular seeds categorized as intermediate due to their limited longevity.
Ewa Marzena Kalemba, Shirin Alipour, Natalia Wojciechowska   +2 more
doaj   +1 more source

Epigenetic Regulation of G6PD Drives Metabolic Reprogramming in Intrahepatic Cholangiocarcinoma. [PDF]

Cancer Sci
This study reveals that tumor‐specific enhancers drive G6PD overexpression in intrahepatic cholangiocarcinoma (ICC), thereby enhancing pentose phosphate pathway activity, maintaining redox homeostasis, and promoting cell proliferation and chemoresistance.
Nakano Y, Tanaka M, Sakamoto T, Hashimoto M, Tobo T, Saito H, Abe T, Ikehara T, Ofuchi T, Kawata K, Masuda T, Ogino T, Uemura M, Eguchi H, Doki Y, Mimori K.   +15 more
europepmc   +2 more sources

Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra [PDF]

, 2007
Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement of whole blood NAD and NADP concentrations. To compare these methods,
Cheung, E, Creeke, P I, Dibari, F, Kyroussis, E, Seal, A J, van den Briel, T   +5 more
core   +2 more sources

Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts

Advanced Science, EarlyView.
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu, Peiji Deng, Qianfan Chen, Qijun Sun, Yanhan Wang, Hongyu Shi, Kang Liang   +6 more
wiley   +1 more source

Magnaporthe oryzae Effector AVR-Pii Helps to Establish Compatibility by Inhibition of the Rice NADP-Malic Enzyme Resulting in Disruption of Oxidative Burst and Host Innate Immunity

Molecules and Cells, 2016
Plant disease resistance occurs as a hypersensitive response (HR) at the site of attempted pathogen invasion. This specific event is initiated in response to recognition of pathogen-associated molecular pattern (PAMP) and subsequent PAMP-triggered ...
Raksha Singh, Sarmina Dangol, Yafei Chen, Jihyun Choi, Yoon-Seong Cho, Jea-Eun Lee, M. Choi, Nam‐Soo Jwa   +7 more
semanticscholar   +1 more source

Dynamic and Static Regulation of Nicotinamide Adenine Dinucleotide Phosphate: Strategies, Challenges, and Future Directions in Metabolic Engineering

Molecules
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial cofactor in metabolic networks. The efficient regeneration of NADPH is one of the limiting factors for productivity in biotransformation processes.
Nana Ding, Zenan Yuan, Lei Sun, Lianghong Yin   +3 more
doaj   +1 more source

Cytosolic Isocitrate Dehydrogenase from Arabidopsis thaliana Is Regulated by Glutathionylation

Antioxidants, 2019
NADP-dependent (Nicotinamide Adénine Dinucléotide Phosphate-dependent) isocitrate dehydrogenases (NADP-ICDH) are metabolic enzymes involved in 2-oxoglutarate biosynthesis, but they also supply cells with NADPH. Different NADP-ICDH genes are
Adnan Khan Niazi, Laetitia Bariat, Christophe Riondet, Christine Carapito, Amna Mhamdi, Graham Noctor, Jean-Philippe Reichheld   +6 more
doaj   +1 more source

A Novel Type II NAD+-Specific Isocitrate Dehydrogenase from the Marine Bacterium Congregibacter litoralis KT71. [PDF]

PLoS ONE, 2015
In most living organisms, isocitrate dehydrogenases (IDHs) convert isocitrate into ɑ-ketoglutarate (ɑ-KG). Phylogenetic analyses divide the IDH protein family into two subgroups: types I and II. Based on cofactor usage, IDHs are either NAD+-specific (NAD-
Ming-Cai Wu, Chang-Qing Tian, Hong-Mei Cheng, Lei Xu, Peng Wang, Guo-Ping Zhu   +5 more
doaj   +1 more source

Stereochemische Entschlüsselung der Strobilurin‐PKS enthüllt die komplexe biosynthetische Logik des iterativen Aufbaus eines EZE‐Triens

Angewandte Chemie, EarlyView.
Die iterative Strobilurin‐PKS baut ein bemerkenswertes EZE‐Trien auf, indem es seine S‐tereoselektvität während der Synthese variiert. Die stereoselektive 2R‐Methylierung des Triketid‐Intermediats durch die C‐terminale C‐Methyltransferase‐Domäne induziert die KR‐ und DH‐Domänen ihre native Stereoselektivität umzukehren und ein Z‐konfiguriertes ...
Maurice Hauser, Jing Pang, Daowan Lai, Yunlong Sun, Hao Yao, Russell J. Cox   +5 more
wiley   +1 more source

Mechanism(s) of action of heavy metals to investigate the regulation of plastidic glucose-6-phosphate dehydrogenase [PDF]

, 2018
The regulation of recombinant plastidic glucose-6P dehydrogenase from Populus trichocarpa (PtP2-G6PDH - EC 1.1.1.49) was investigated by exposing wild type and mutagenized isoforms to heavy metals.
Cardi, Manuela, DE LILLO, Alessia, Esposito, Sergio, Landi, Simone   +3 more
core   +2 more sources