Results 101 to 110 of about 122,170 (318)
In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma. [PDF]
, 2019 Dysregulation in NAD+/NADH levels is associated with increased cell division and elevated levels of reactive oxygen species in rapidly proliferating cancer cells.
Batsios, Georgios +7 more
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NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression
Nature Communications, 2019 Cancer cells respond differently to inhibitors of Poly (ADP-ribose) polymerase. Here the authors reveal that ovarian cancer cells with higher cellular NADP+ levels are more sensitive to clinically relevant PARP1 inhibitors and show that NADP+ act as an ...
Chunjing Bian +9 more
doaj +1 more source
Limnology and Oceanography, EarlyView.Abstract Continental shelf ecosystems support diverse phytoplankton communities that contribute to global primary productivity. Iron is an important micronutrient controlling the growth of marine phytoplankton, but its role in influencing phytoplankton ecophysiology in western boundary continental shelf ecosystems is understudied.
Lucy E. Quirk +2 more
wiley +1 more source
The mechano-chemistry of cytoskeletal force generation [PDF]
, 2014 In this communication, we propose a model to study the non-equilibrium process by which actin stress fibers develop force in contractile cells. The emphasis here is on the non-equilibrium thermodynamics, which is necessary to address the mechanics as ...
Garikipati, Krishna, Maraldi, Mirko
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Plant defense strategies: The dual armor of disease resistance and tolerance
New Plant Protection, EarlyView.Plants employ dual strategies against pathogens: Resistance limits invasion via immune responses, whereas tolerance mitigates damage to sustain growth—together enhancing survival under infections. Abstract Pathogen infections pose a significant threat to plant health, global food security, and ecosystems.
Zhijuan Tang +3 more
wiley +1 more source
ChemistryOpen, EarlyView.Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan +3 more
wiley +1 more source
Manual for starch gel electrophoresis: A method for the detection of genetic variation [PDF]
, 1987 The procedure to conduct horizontal starch gel electrophoresis on enzymes is described in detail. Areas covered are (I) collection and storage of specimens, (2) preparation of tissues, (3) preparation of a starch gel, (4) application of enzyme extracts ...
Aebersold, Paul B. +4 more
core
Plastidial NADP-Malic Enzymes from grasses: unravelling the way to the C4 specific isoforms [PDF]
, 2013 Malic enzyme is present in many plant cell compartments such as plastids, cytosol and mitochondria. Particularly relevant is the plastidial isoform that participates in the C4 cycle providing CO2 to RuBisCO in C4 species.
Alvarez, Clarisa Ester +3 more
core +2 more sources
Biomolecules, 2019 Giardia lambia is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that G. lamblia exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate ...
Laura Morales-Luna +17 more
doaj +1 more source
CHANGES IN THE LEVELS OF NICOTINAMIDE NUCLEOTIDES AND IN ACTIVITIES OF NADP-DEPENDENT DEHYDROGENASES AFTER A BRIEF ILLUMINATION OF RED LIGHT [PDF]
, 1969 Tadashi Fujii, Noriaki Kondo
openalex +1 more source