Results 121 to 130 of about 141,947 (341)
Scientific Reports, 2016 7α-hydroxysteroid dehydrogenase (7α-HSDH) can catalyse the oxidation of C7 α-OH of the steroid nucleus in the bile acid metabolism. In the paper we determined the crystal structure of 7α-HSDH from Clostridium absonum (CA 7α-HSDH) complexed with ...
D. Lou +6 more
semanticscholar +1 more source
European Journal of Organic Chemistry, EarlyView.This brief compendium summarizes the most successful asymmetric hydrogenation strategies for the preparation of chiral monocyclic γ‐lactone derivatives from keto acids and keto esters, with emphasis on their relevance for large‐scale production and high enatioselectivities. This article provides a brief compendium on the production of chiral monocyclic
Marta Feliz, Maria J. Sabater
wiley +1 more source
Magnesium deficiency-induced changes in organic acid metabolism of Citrus sinensis roots and leaves
Biologia Plantarum, 2013 Organic acid (OA) metabolisms are of fundamental importance but very limited data are available on the responses of plant OA metabolisms to Mg-deficiency. Seedlings of Citrus sinensis (L.) Osbeck cv. Xuegan were irrigated with Mg-deficient (0, 50, or 500
L.T. Yang +5 more
doaj +1 more source
The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones [PDF]
, 2017 Vertebrate rod and cone photoreceptors require continuous supply of chromophore for regenerating their visual pigments after photoactivation. Cones, which mediate our daytime vision, demand a particularly rapid supply of 11-cis retinal chromophore in ...
Cornwall, M. Carter +3 more
core +2 more sources
Scientific Reports, 2015 Eukaryotic metabolism is organised in complex networks of enzyme catalysed reactions which are distributed over different organelles. To quantify the compartmentalised reactions, quantitative measurements of relevant physiological variables in different ...
Jinrui Zhang +7 more
semanticscholar +1 more source
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert +5 more
wiley +1 more source
Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
International Journal of Cancer, EarlyView.Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
Plastidial NADP-Malic Enzymes from grasses: unravelling the way to the C4 specific isoforms [PDF]
, 2013 Malic enzyme is present in many plant cell compartments such as plastids, cytosol and mitochondria. Particularly relevant is the plastidial isoform that participates in the C4 cycle providing CO2 to RuBisCO in C4 species.
Alvarez, Clarisa Ester +3 more
core +2 more sources
A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number
, 2017 NADP+-dependent enzymes are important in many biocatalytic processes to generate high-value chemicals for the pharmaceutical and food industry; hence, a cost-effective, efficient, and environmentally friendly recycling system for the relatively expensive
Antonio Angelastro +3 more
semanticscholar +1 more source
Journal of Biophotonics, EarlyView.The efficient discrimination of a hepatic cancer lesion and its surgical margin using autofluorescence lifetime imaging is presented. White light image of the specimen on the left and the augmented image with fluorescence lifetime data on the right.
D. Suraci +9 more
wiley +1 more source