Results 21 to 30 of about 424,484 (404)
Antioxidants, 2021 Alzheimer’s disease (AD) is one of the main human dementias around the world which is constantly increasing every year due to several factors (age, genetics, environment, etc.) and there are no prevention or treatment options to cure it.
Leticia Guadalupe Fragoso-Morales +2 more
doaj +1 more source
NADPH Oxidases in Pain Processing
Antioxidants, 2022 Inflammation or injury to the somatosensory nervous system may result in chronic pain conditions, which affect millions of people and often cause major health problems. Emerging lines of evidence indicate that reactive oxygen species (ROS), such as superoxide anion or hydrogen peroxide, are produced in the nociceptive system during chronic inflammatory
Wiebke Kallenborn-Gerhardt +2 more
openaire +4 more sources
Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. [PDF]
PLoS ONE, 2011 NADPH oxidase is a crucial enzyme in mediating antimicrobial host defense and in regulating inflammation. Patients with chronic granulomatous disease, an inherited disorder of NADPH oxidase in which phagocytes are defective in generation of reactive ...
R Robert Vethanayagam +10 more
doaj +1 more source
Regulation of Plant NADPH Oxidase [PDF]
Plant Signaling & Behavior, 2007 The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant-microorganisms interactions.
Elmayan, Taline, Simon-Plas, Françoise
openaire +5 more sources
Antioxidants, 2021 Background: Formyl peptide receptor 2 (FPR2) is involved in the pathogenesis of chronic inflammatory diseases, being activated either by pro-resolving or proinflammatory ligands.
Rosario Ammendola +3 more
doaj +1 more source
Skeletal muscle NADPH oxidase is increased and triggers stretch-induced damage in the mdx mouse. [PDF]
PLoS ONE, 2010 Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice.
Nicholas P Whitehead +3 more
doaj +1 more source
Redox modulation of FAK controls melanoma survival--role of NOX4. [PDF]
PLoS ONE, 2014 Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear.
Cristiane Ribeiro-Pereira +5 more
doaj +1 more source
Electrochemical tuning of alcohol oxidase and dehydrogenase catalysis via biosensing towards butanol-1 detection in fermentation media [PDF]
Biosensors and Bioelectronics 170 (2020) 112702, 2021 A novel approach for electrochemical tuning of alcohol oxidase (AOx) and alcohol dehydrogenase (ADH) biocatalysis towards butanol-1 oxidation by incorporating enzymes in various designs of amperometric biosensors is presented. The biosensors were developed by using commercial graphene oxide-based screen-printed electrodes and varying enzyme producing ...
arxiv +1 more source
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Circulation Research, 1994 The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are incompletely understood but include the generation of molecules likely to affect oxidase activity.
K. Griendling +3 more
semanticscholar +1 more source
Effects of Iodonium Analogs on Nadph Oxidase 1 in Human Colon Cancer Cells
Antioxidants, 2021 Recent studies suggest that of the molecules postulated to function as inhibitors of the NADPH oxidase family of enzymes iodonium analogs known to broadly interfere with flavin dehydrogenase function demonstrate mechanistic validity as NADPH oxidase ...
Krishnendu K. Roy +2 more
doaj +1 more source