Results 21 to 30 of about 442,921 (391)
Redox modulation of FAK controls melanoma survival--role of NOX4. [PDF]
PLoS ONE, 2014 Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear.
Cristiane Ribeiro-Pereira +5 more
doaj +1 more source
Effects of Iodonium Analogs on Nadph Oxidase 1 in Human Colon Cancer Cells
Antioxidants, 2021 Recent studies suggest that of the molecules postulated to function as inhibitors of the NADPH oxidase family of enzymes iodonium analogs known to broadly interfere with flavin dehydrogenase function demonstrate mechanistic validity as NADPH oxidase ...
Krishnendu K. Roy +2 more
doaj +1 more source
Expression and modulation of an NADPH oxidase in mammalian astrocytes [PDF]
, 2005 Amyloid β peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the NADPH oxidase [diphenylene iodonium (DPI) and apocynin].
Abramov, A.Y. +5 more
core +1 more source
NADPH Oxidases in Vascular Pathology [PDF]
Antioxidants & Redox Signaling, 2014 Reactive oxygen species (ROS) play a critical role in vascular disease. While there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases play a central role. They are a source of "kindling radicals," which affect other enzymes, such as nitric oxide synthase endothelial nitric oxide synthase or xanthine oxidase.
Anna, Konior +3 more
openaire +3 more sources
Acta Societatis Botanicorum Poloniae, 2017 Cadmium-induced oxidative burst is partially mediated by NADPH oxidase. The aim of the present research was to evaluate the role of NADPH oxidase in soybeans’ response to short-term cadmium stress.
Jagna Chmielowska-Bąk +6 more
doaj +1 more source
NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice. [PDF]
PLoS ONE, 2016 The role of the reactive oxygen species-producing NADPH oxidase family of enzymes in the pathology of influenza A virus infection remains enigmatic. Previous reports implicated NADPH oxidase 2 in influenza A virus-induced inflammation. In contrast, NADPH
Amelia R Hofstetter +16 more
doaj +1 more source
Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]
, 2008 The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Cecchi, Marie +5 more
core +3 more sources
Regulation of Plant NADPH Oxidase [PDF]
Plant Signaling & Behavior, 2007 The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant-microorganisms interactions.
Elmayan, Taline, Simon-Plas, Françoise
openaire +3 more sources
Phosphatidylinositol 3-kinase plays a vital role in regulation of rice seed vigor via altering NADPH oxidase activity. [PDF]
PLoS ONE, 2012 Phosphatidylinositol 3-kinase (PI3K) has been reported to be important in normal plant growth and stress responses. In this study, it was verified that PI3K played a vital role in rice seed germination through regulating NADPH oxidase activity ...
Jian Liu, Jun Zhou, Da Xing
doaj +1 more source
Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung [PDF]
, 2014 Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS).
Anderson +23 more
core +3 more sources