Results 141 to 150 of about 48,906 (319)

The Hidden Architects: Nitric Oxide and Redox Dynamics in Plant Stem Cell Homeostasis

BioEssays, EarlyView.
This review highlights the dynamic interplay between nitric oxide (NO) and reactive oxygen species (ROS) in regulating plant stem cell renewal and differentiation. NO and ROS integrate intrinsic factors like epigenetic and hormonal signals with extrinsic cues, including environmental stress and nutrient‐TOR signaling, to maintain meristem function and ...
Jian Zeng, Xin'Ai Zhao, Jan U. Lohmann
wiley   +1 more source

NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors. [PDF]

J Med Chem, 2023
Cipriano A, Viviano M, Feoli A, Milite C, Sarno G, Castellano S, Sbardella G.   +6 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Involvement of GTP in cell-free activation of neutrophil NADPH oxidase. Studies with GTP analogues [PDF]

, 1992
E Klinger, Irit Aviram
openalex   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

NOX/NADPH Oxidase, the Superoxide-Generating Enzyme: Its Transcriptional Regulation and Physiological Roles

Journal of Pharmacological Sciences, 2010
NADPH oxidase is a superoxide (O2−)-generating enzyme first identified in phagocytes that shows bactericidal activities. It has been reported that O2− is also produced in an NADPH-dependent manner in non-phagocytes. In the last decade, non-phagocyte-type
Masato Katsuyama
doaj  

Relationship between phosphorylation and translocation to the plasma membrane of p47phox and p67phox and activation of the NADPH oxidase in normal and Ca2+-depleted human neutrophils [PDF]

, 1993
Stefano Dusi, Vittorina Della Bianca, Mirosława Grzeskowiak, Filippo Rossi   +3 more
openalex   +1 more source

Synthesis, Characterization, Biological Evaluation, DFT Calculations, and Molecular Docking Study of Transition Metal Complexes Derived From a Schiff Base Ligand

Chemistry &Biodiversity, EarlyView.
ABSTRACT The escalating global challenge of antibiotic resistance amid rising oxidative stress emphasizes the critical necessity for innovative antimicrobial strategies. This study, reported synthesis of Schiff base ligand, (Z)‐2‐[(4‐nitrobenzylidene)amino]phenol (HL), derived from condensation between 2‐aminophenol and 4‐nitrobenzaldehyde, and it Co ...
Ibrahim Waziri, Olaide O. Wahab, Grema A. Mala, Musa B. Ismaila, Usman Umaru, Mostafa S. Abd El‐Maksoud, Ibrahim M. Wakil, Tunde L. Yusuf   +7 more
wiley   +1 more source

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. [PDF]

, 2019
People heterozygous for an activating mutation in protein kinase G1 (PRKG1, p.Arg177Gln) develop thoracic aortic aneurysms and dissections (TAAD) as young adults.
Boss, Gerry R, Casteel, Darren E, Dalton, Nancy D, Gu, Yusu, Kalyanaraman, Hema, Lee, Seunghoe, Makino, Ayako, Milewicz, Dianna M, Patel, Hemal H, Peterson, Kirk L, Pilz, Renate B, Schilling, Jan M, Schwaerzer, Gerburg K, Wahwah, Nisreen, Zhang, Qian, Zhuang, Shunhui   +15 more
core   +1 more source

The role of dual oxidases in physiology and cancer

Genetics and Molecular Biology
NOX/DUOX enzymes are transmembrane proteins that carry electrons through biological membranes generating reactive oxygen species. The NOX family is composed of seven members, which are NOX1 to NOX5 and DUOX1 and 2.
Caroline Coelho de Faria, Rodrigo Soares Fortunato   +1 more
doaj   +1 more source