Using the transgenic rat for adenocarcinoma of prostate (TRAP) model, apocynin, an inhibitor of NADPH oxidase, was shown to suppress prostate carcinogenesis. Representative histopathological finding for lesions in the lateral prostates of TRAP rats treated with 500 mg/L apocynin [PDF]
, 2013 Shugo Suzuki +7 more
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Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases. [PDF]
Cells, 2023 Guse AH.
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Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1996 Henderson, Lydia M., Chappell, J.Brian
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Calcium signaling in plant defense
New Plant Protection, EarlyView.Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley +1 more source
Nox, Nox, Are You There? The Role of NADPH Oxidases in the Peripheral Nervous System. [PDF]
Antioxid Redox Signal, 2022 Eid SA +3 more
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Plasmodesmata‐located proteins: The molecular hubs in noncell‐autonomous immunity
New Plant Protection, EarlyView.Plasmodesmata serve as critical battlefields for plant immunity, regulated by diverse proteins. This article provides a comprehensive review of the regulatory mechanisms, challenges, and future directions concerning proteins located within plasmodesmata and their roles in plant defense responses.
Zheng Wu, Xiaoyi Shan
wiley +1 more source
The role of NADPH oxidases in infectious and inflammatory diseases. [PDF]
Redox Biol, 2021 Taylor JP, Tse HM.
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NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology
, 2013 Jennifer L. Meitzler +8 more
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Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. [PDF]
, 1996 Sanjay Rajagopalan +6 more
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