Results 191 to 200 of about 296,542 (336)
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho+10 more
wiley +1 more source
Involvement of NADPH oxidases in the Na/K‑ATPase/Src/ROS oxidant amplification loop in renal fibrosis. [PDF]
Zhang H, Lai F, Cheng X, Wang Y.
europepmc +1 more source
Involvement of GTP in cell-free activation of neutrophil NADPH oxidase. Studies with GTP analogues [PDF]
E Klinger, Irit Aviram
openalex +1 more source
NADPH oxidases: an overview from structure to innate immunity-associated pathologies
Arvind Panday+3 more
semanticscholar +1 more source
Hydrochlorothiazide plus combined exercise training provides superior benefits compared to medication alone in female spontaneously hypertensive rats subjected to ovarian hormone deprivation. This combined approach significantly reduced blood pressure variability, improved inflammatory and redox profiles, and provided functional and morphological ...
Pietra Petrica Neves+6 more
wiley +1 more source
Prolonged fasting and fibrate treatment induce peroxisomal β‐oxidation and lead to excessive generation of hydrogen peroxide, which stimulates ethanol metabolism and significantly increases the formation of acetaldehyde; further oxidation of acetaldehyde into acetate remarkably elevates the mitochondrial ratio of NADH/NAD+ and causes feedback ...
Yida Zhang+6 more
wiley +1 more source
Nutrient‐induced changes in root respiration in 10 woody plant species
Read the free Plain Language Summary for this article on the Journal blog. Abstract Nitrogen (N) and phosphorus (P) are soil macronutrients that influence ecosystem productivity through strong impacts on plant metabolism. The influence of nutrient supply on the relationships between leaf respiration rate (R) and leaf N concentration ([N]) has been ...
Deping Zhai+9 more
wiley +1 more source
Role of NADPH Oxidases in Blood-Brain Barrier Disruption and Ischemic Stroke. [PDF]
Hernandes MS, Xu Q, Griendling KK.
europepmc +1 more source
ABSTRACT Introduction Activated neutrophils play a crucial role in the development of neutrophilic dermatoses, including pustular psoriasis. Adsorptive granulocyte and monocyte apheresis (GMA) is an effective treatment for skin disorders. Although previous basic research has demonstrated neutrophil activation, no efficient method exists to assess it in
Yuko Higashi+8 more
wiley +1 more source