Results 191 to 200 of about 296,542 (336)

NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic

open access: yesSmall, EarlyView.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho   +10 more
wiley   +1 more source

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

open access: yesCellular & Molecular Immunology, 2014
Arvind Panday   +3 more
semanticscholar   +1 more source

Hydrochlorothiazide combined with exercise training attenuates blood pressure variability and renal dysfunctions in an experimental model of hypertension and ovarian hormone deprivation

open access: yesFASEB BioAdvances, Volume 7, Issue 4, April 2025.
Hydrochlorothiazide plus combined exercise training provides superior benefits compared to medication alone in female spontaneously hypertensive rats subjected to ovarian hormone deprivation. This combined approach significantly reduced blood pressure variability, improved inflammatory and redox profiles, and provided functional and morphological ...
Pietra Petrica Neves   +6 more
wiley   +1 more source

Induction of Peroxisomal β‐Oxidation as a Critical Mechanism for Ethanol‐Induced Hepatic Triglyceride Accumulation

open access: yesFASEB BioAdvances, EarlyView.
Prolonged fasting and fibrate treatment induce peroxisomal β‐oxidation and lead to excessive generation of hydrogen peroxide, which stimulates ethanol metabolism and significantly increases the formation of acetaldehyde; further oxidation of acetaldehyde into acetate remarkably elevates the mitochondrial ratio of NADH/NAD+ and causes feedback ...
Yida Zhang   +6 more
wiley   +1 more source

Nutrient‐induced changes in root respiration in 10 woody plant species

open access: yesFunctional Ecology, Volume 39, Issue 4, Page 1128-1139, April 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Nitrogen (N) and phosphorus (P) are soil macronutrients that influence ecosystem productivity through strong impacts on plant metabolism. The influence of nutrient supply on the relationships between leaf respiration rate (R) and leaf N concentration ([N]) has been ...
Deping Zhai   +9 more
wiley   +1 more source

Evaluation of Neutrophil Activity Before and After Granulocyte and Monocyte Adsorptive Apheresis in Patients With Pustular Psoriasis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Activated neutrophils play a crucial role in the development of neutrophilic dermatoses, including pustular psoriasis. Adsorptive granulocyte and monocyte apheresis (GMA) is an effective treatment for skin disorders. Although previous basic research has demonstrated neutrophil activation, no efficient method exists to assess it in
Yuko Higashi   +8 more
wiley   +1 more source

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