Results 71 to 80 of about 28,923 (304)
Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023 Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman +6 more
wiley +1 more source
Nanowire Growth for Sensor Arrays [PDF]
, 2003 A design concept for nanowire-based sensors and arrays is described. The fabrication technique involves electrodeposition to directly grow nanowires between patterned thin film contact electrodes. To prove our concept, we have electrodeposited 1-mm diameter Pd single wires and small arrays.
arxiv +1 more source
NADPH oxidases in the arbuscular mycorrhizal symbiosis [PDF]
Plant Signaling & Behavior, 2016 Plant NADPH oxidases are the major source of reactive oxygen species (ROS) that plays key roles as both signal and stressor in several plant processes, including defense responses against pathogens. ROS accumulation in root cells during arbuscular mycorrhiza (AM) development has raised the interest in understanding how ROS-mediated defense programs are
BELMONDO, SIMONE +5 more
openaire +4 more sources
Therapeutic Black Phosphorus Nanosheets Elicit Neutrophil Response for Enhanced Tumor Suppression
Advanced Science, EarlyView.This study explores black phosphorus (BP) nanosheets in breast cancer models, showing their ability to inhibit tumor growth. BP‐PEG enhances immune responses by promoting neutrophil recruitment and reprogramming tumor‐associated neutrophils to an antitumor phenotype, boosting both innate and adaptive antitumor immune activities.
Jing Wang +10 more
wiley +1 more source
Respiratory Research, 2005 Background The sources and measurement of reactive oxygen species (ROS) in intact organs are largely unresolved. This may be related to methodological problems associated with the techniques currently employed for ROS detection.
Schudt Christian +12 more
doaj +1 more source
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death.
PLoS Biology, 2021 Several studies have revealed a correlation between chronic inflammation and nicotinamide adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown.
Francisco J Martínez-Morcillo +17 more
doaj +1 more source
Advanced Science, EarlyView.During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu +13 more
wiley +1 more source
PROTEOMICS, Volume 22, Issue 23-24, December 2022., 2022 Abstract The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is characterised by primary abnormalities in the membrane cytoskeletal component dystrophin. The almost complete absence of the Dp427‐M isoform of dystrophin in skeletal muscles renders contractile fibres more susceptible to progressive degeneration and a leaky ...
Paul Dowling +3 more
wiley +1 more source
BMC Pulmonary Medicine, 2021 Objective Acute lung injury (ALI) is characterized by inflammation and oxidative stress. Nuclear factor-kappaB (NF-κB) mediates the expression of various inflammation-related genes, including the NADPH oxidase family.
Weijing Wu +8 more
doaj +1 more source
Advanced Science, EarlyView.This study explores the role of Mitotic Spindle Positioning (MISP) as a key inhibitor of ferroptosis in non‐small cell lung cancer (NSCLC). MISP upregulation in NSCLC tissues leads to ferroptosis resistance, promoting cell proliferation. Mechanistically, MISP suppresses Hippo signaling via MST1/2 kinases, activating YAP and enhancing SLC7A11 expression,
Fuquan Zhang +6 more
wiley +1 more source