Results 171 to 180 of about 143,942 (291)

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues   +7 more
wiley   +1 more source

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

open access: yesCell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You   +3 more
wiley   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

open access: yesCell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo   +6 more
wiley   +1 more source

Associations between steatotic liver disease subtypes and incident diabetes in young Korean adults: A nationwide cohort study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The impact of steatotic liver disease (SLD) subtypes on incident type 2 diabetes remains unclear. We investigated the association of metabolic dysfunction‐associated steatotic liver disease (MASLD), MetALD (MASLD with moderate alcohol consumption), and alcohol‐related liver disease (ALD) with incident type 2 diabetes in Korean adults aged
Goh Eun Chung   +6 more
wiley   +1 more source

Population‐based cohort validation and replication reveals limited generalizability of cluster‐based MASLD subtypes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims MASLD, defined as a steatotic liver disease in the presence of one or more cardiometabolic risk factors and the absence of harmful alcohol intake, exhibits substantial heterogeneity complicating risk stratification. A prior clustering model proposed liver‐specific and cardiometabolic subtypes, yet its generalizability and prognostic ...
Junjie Wu   +3 more
wiley   +1 more source

Predictors of High Cardiovascular Risk Among Nonobese Patients with Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease in a Chinese Population

open access: yesDiabetes, Metabolic Syndrome and Obesity
Shuping Ruan,* Xiaoqing Yuan,* Juan Liu, Qing Zhang, Xinhua Ye Department of Endocrinology, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou Medical Center, Nanjing Medical University, Changzhou, People’s ...
Ruan S, Yuan X, Liu J, Zhang Q, Ye X
doaj  

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