Results 171 to 180 of about 94,270 (218)

White blood cell count to platelet ratio (WBC/PLT) is associated with adverse lipid parameters and lower antioxidants intake in patients with NAFLD. [PDF]

Sci Rep
El-Sehrawy AAMA, Salah AM, Labib S, Elsayed HM, Alanazi MA, Abohassan M, Hegazy GA, Yusuf SM, ELmazny GM, Kandil I.   +9 more
europepmc   +1 more source

Lipid and Foam Cell Accumulation as Novel Pathological Features of Benign Prostatic Hyperplasia

The Prostate, Volume 86, Issue 10, Page 1157-1169, July 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) encompasses a heterogeneous set of pathological processes that instigate lower urinary tract symptoms (LUTS). Using a mouse model of steroid hormone imbalance–induced lower urinary tract dysfunction, we identified luminal lipid‐laden foamy macrophages, although their presence and contribution to ...
Dita Julianingsih, Samara V. Silver, Thaissa Horne, Kasun Gunawardena, Savannah Ward, Alicia Malewska, Douglas Strand, Julius Nyalwidhe, Ilya Sobol, Petra Popovics   +9 more
wiley   +1 more source

Failure of Hepatic Insulin Clearance via CEACAM1-Mediated Endocytosis: The Missing Physiological Link Between Proinsulin Misfolding, Hyperinsulinemia, and Metabolic Complications in Type 2 Diabetes, Obesity, and NAFLD. [PDF]

Probl Endokrinol (Mosk)
Akl MM, Ahmed A.
europepmc   +1 more source

Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Mice

Aging Cell, Volume 25, Issue 7, July 2026.
Aging and Western diet synergistically impair hepatic thyroid hormone signaling through decreased Dio1 and increased Dio3 activity, depleting intrahepatic T4 and T3 in senescent hepatocytes. This thyroid hormone deficit drives inflammation, fibrosis, and accelerated MASLD progression.
Xinru Zhang, Madhulika Tripathi, Chun Ting Goh, Chee Seng Chan, Anita Boelen, Paul M. Yen, Brijesh Kumar Singh, Eveline Bruinstroop   +7 more
wiley   +1 more source

Pachymic Acid Alleviates Non-Alcoholic Fatty Liver Disease via FGF21-Mediated Inhibition of the p38 MAPK Pathway. [PDF]

Food Sci Nutr
Nie L, Ma D, Deng X, Erbu A, Wang F, Shi W, Li Z, Cui H, Wen W.   +8 more
europepmc   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, Volume 105, Issue 1, Page 42-50, July 2026.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

Integrated Bulk and Single-Cell RNA-Seq Analysis Reveals Transcriptional Activation of PTGS2 by FOS in Progression From T2DM to T2DM-Associated NAFLD. [PDF]

J Cell Mol Med
Lin R, Xu L, Zhou Y, Fan Y, Xie H, Li W, Hu T, Liu C.   +7 more
europepmc   +1 more source

Association of Semaglutide Treatment With Liver Cirrhosis and Hepatocellular Carcinoma in Type 2 Diabetes: A Population‐Based Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5704-5714, July 2026.
ABSTRACT Background Metabolic dysfunction–associated steatotic liver disease is common among individuals with type 2 diabetes mellitus and substantially increases the risk of liver cirrhosis and hepatocellular carcinoma. Effective therapies that improve metabolic control while preventing advanced liver outcomes are limited.
Assaf Issachar, Talish Razi, Ilya Borochov, Hadar Duskin Bitan, Ronen Arbel   +4 more
wiley   +1 more source

Serum free and bioavailable rather than total testosterone is associated with the progression of non-alcoholic fatty liver disease in postmenopausal women: a prospective study. [PDF]

Front Endocrinol (Lausanne)
Wang X, Li Q, Lin J, Pan Z, Zeng Y, Shen T, Chen X, Ling W, Chen Y.   +8 more
europepmc   +1 more source