Results 231 to 240 of about 143,942 (291)

Efficacy of Pediococcus acidilactici PA53 in preventing high-fat diet-induced non-alcoholic fatty liver disease in mice. [PDF]

Front Immunol
Niu Y, Liu P, Chen Y, Yao Y, Bu S.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Diagnosis and Management of Pediatric Non-Alcoholic Fatty Liver Disease: An Overview. [PDF]

Metabolites
Dop D, Pădureanu V, Pădureanu R, Niculescu CE, Niculescu ȘA, Marcu IR.   +5 more
europepmc   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

The Therapeutic Effect and Mechanism of <i>Lactobacillus gardneri</i> on Nonalcoholic Fatty Liver Disease. [PDF]

J Microbiol Biotechnol
Zhu K, Xiang J, Lu F, Wang J, Zhang Y, Feng H, Xiang X.   +6 more
europepmc   +1 more source

Tenofovir Alafenamide Fumarate Reduces Virological Replication in HBeAg‐Negative Patients With Normal Alanine Aminotransferase: A 48‐Week Randomised Controlled Trial

Journal of Viral Hepatitis, Volume 33, Issue 3, March 2026.
ABSTRACT The optimal strategy for chronic hepatitis B virus (HBV) infected patients with negative hepatitis B e‐antigen (HBeAg) and normal alanine aminotransferase (ALT) remains uncertain. This study aimed to evaluate the safety and efficacy of tenofovir alafenamide fumarate (TAF) treatment in this patient population.
Qiumin Luo, Wenxiong Xu, Yeqiong Zhang, Xiangyong Li, Jing Lai, Jianguo Li, Xingrong Zheng, Hong Deng, Lubiao Chen, Xiang Zhu, Chan Xie, Liang Peng   +11 more
wiley   +1 more source

<i>Schisandra chinensis</i> alleviates Hypertriglyceridemia in nonalcoholic fatty liver disease by modulating the gut microbiota and hepatic lipid metabolism: identification of its active fractions. [PDF]

Front Pharmacol
Li Q, Feng M, Luo Q, Ye CY, Luo YK, Xu LY.   +5 more
europepmc   +1 more source

Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Workflow for discovering parasitological and molecular changes related to Schistosoma mansoni infection. ABSTRACT Parasites can induce changes in their hosts, favoring the success of the infection and its development at each stage of their life cycle.
Sheila de Andrade Penteado Corrêa, Cauã da Silva Oliveira Teodoro, João Paulo Luz da Silva, Fabio Queiroz, Tayná Dandara do Amaral, Silmara Marques Allegretti, Fernanda Silva de Oliveira, Rafaela Ferraz Teixeira, Lizandra Maia de Sousa, Sílvio Roberto Consonni, Matheus de Souza Gomes, Christoph Grunau, Fernanda Janku Cabral   +12 more
wiley   +1 more source