Results 31 to 40 of about 147,468 (308)

The Emerging Role of Disturbed CoQ Metabolism in Nonalcoholic Fatty Liver Disease Development and Progression [PDF]

, 2015
Although non-alcoholic fatty liver disease (NAFLD), characterised by the accumulation of triacylglycerol in the liver, is the most common liver disorder, the causes of its development and progression to the more serious non-alcoholic steatohepatitis ...
Elena Bravo, Kathleen Botham, Mariarosaria Napolitano, Sumimoto   +3 more
core   +3 more sources

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Body mass index and risk of non-alcoholic fatty liver disease: two electronic health record prospective studies [PDF]

, 2015
Context: The relationship between rising body mass index (BMI) and prospective risk of non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH) is virtually absent. Objective: Determine the extent of the association between BMI
Bonato, Vinicius, Desai, Jigar, Gill, Jason M.R., Hyde, Craig, Kabadi, Shaum, Loomis, A. Katrina, Preiss, David, Sattar, Naveed, St. Louis, Matthew, Waterworth, Dawn, Welsh, Paul   +10 more
core   +2 more sources

NAFLD: A multisystem disease

Journal of Hepatology, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries that is predicted to become also the most frequent indication for liver transplantation by 2030. Over the last decade, it has been shown that the clinical burden of NAFLD is not only confined to liver-related morbidity and mortality, but ...
CD Byrne, TARGHER, Giovanni
openaire   +4 more sources

Hyperinsulinemia predisposes to NAFLD [PDF]

Indian Journal of Clinical Biochemistry, 2008
Metabolic syndrome contributes to pathogenesis of Type-2 diabetes and CAD. Insulin Resistance is the key factor of metabolic syndrome implicated in development of Non Alcoholic Fatty Liver Disease (NAFLD). In present study we have investigated the prevalence of NAFLD in metabolic syndrome and contribution of metabolic risk factors in causation of NAFLD
Sandhya, Mishra, Dharamveer, Yadav, Monika, Gupta, Hemant, Mishra, Praveen, Sharma   +4 more
openaire   +2 more sources

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

Hepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef, Milan J. Sonneveld, Maryam Kavousi, M. Arfan Ikram, Robert A. de Man, Robert J. de Knegt   +5 more
wiley   +1 more source

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality

Hepatology, EarlyView., 2022
Visualisation of the study desgin, main results and key findings. Abstract Background and Aims MAFLD often cooccurs with excessive alcohol consumption, while its prognostic value in this group remains unclear. We aimed to study the mortality risk of MAFLD in relation to excessive alcohol consumption and its potential interactions.
Laurens A. van Kleef, Robert J. de Knegt, Willem Pieter Brouwer   +2 more
wiley   +1 more source

Radiomics‐based model for accurately distinguishing between severe acute respiratory syndrome associated coronavirus 2 (SARS‐CoV‐2) and influenza A infected pneumonia

MedComm, 2020
Clinicians have been faced with the challenge of differentiating between severe acute respiratory syndrome associated coronavirus 2 (SARS‐CoV‐2) infected pneumonia (NCP) and influenza A infected pneumonia (IAP), a seasonal disease that coincided with the
Qi‐Qiang Zeng, Kenneth I. Zheng, Jun Chen, Zheng‐Hao Jiang, Tian Tian, Xiao‐Bo Wang, Hong‐Lei Ma, Ke‐Hua Pan, Yun‐Jun Yang, Yong‐Ping Chen, Ming‐Hua Zheng   +10 more
doaj   +1 more source

Association between thyroid function and assessment of hepatic fat and iron contents by magnetic resonance imaging

Endocrine Connections, 2022
The associations of thyroid function parameters with non-alcoholic fatty liver disease (NAFLD) and hepatic iron overload are not entirely clear. We have cross-sectionally investigated these associations among 2734 participants of two population-based ...
Till Ittermann, Rehman Mehmood Khattak, Marcello R P Markus, Jens-Peter Kühn, Marie-Luise Kromrey, Giovanni Targher, Antje Steveling, Matthias Nauck, Henry Völzke   +8 more
doaj   +1 more source

Similar reduction of cholesterol-adjusted Vitamin E serum levels in simple steatosis and non-alcoholic steatohepatitis [PDF]

, 2015
OBJECTIVES: Reduced vitamin E levels have been reported in patients with non-alcoholic steatohepatitis (NASH), but no conclusive data on patients with simple steatosis (SS) are available. Aim of this study was to investigate the association betweenserum
Angelico, Francesco, Baratta, Francesco, Bucci, Tommaso, Cangemi, Roberto, Carnevale, Roberto, DEL BEN, Maria, Labbadia, Giancarlo, Nocella, Cristina, Pani, Arianna, Pastori, Daniele, Pignatelli, Pasquale, Polimeni, Licia, Scardella, Laura, Violi, Francesco   +13 more
core   +1 more source