Results 51 to 60 of about 1,762 (164)
Nailfold Microhemorrhage Segmentation with Modified U-Shape Convolutional Neural Network
Applied Sciences, 2022 Nailfold capillaroscopy is a reliable way to detect and analyze microvascular abnormalities. It is safe, simple, noninvasive, and inexpensive. Among all the capillaroscopic abnormalities, nailfold microhemorrhages are closely associated with early ...
Ruiqi Liu +6 more
doaj +1 more source
Experimental Dermatology, Volume 35, Issue 2, February 2026.This study demonstrates that tocilizumab (TCZ) treatment promotes microvascular recovery in systemic sclerosis (SSc), as evidenced by increased capillary density and that this improvement in vasculopathy is closely associated with enhanced pulmonary function.
Yuichiro Segawa +6 more
wiley +1 more source
Arthritis Care &Research, Volume 78, Issue 1, Page 106-112, January 2026.Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech +4 more
wiley +1 more source
Respirology Case Reports, Volume 14, Issue 1, January 2026.We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Hiro Ikeda +3 more
wiley +1 more source
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?
European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa +7 more
wiley +1 more source
Nailfold Capillaroscopy in Buerger’s Disease: An Useful Tool?
European Journal of Rheumatology, 2014 Abstract Thromboangiitis obliterans (TAO, or Buerger’s disease) is a rare inflammatory vasculitis that commonly involves small and medium-sized arteries of the extremities of tobacco smokers between the ages of 25 and 50 years. Although the diagnosis is based on the clinical picture and angiographic findings, we studied the microvascular involvement ...
Giacomo Maria, Guidelli +3 more
openaire +2 more sources
Pembrolizumab‐Induced Morphea in a Patient With Metastatic Urothelial Carcinoma
Case Reports in Urology, Volume 2026, Issue 1, 2026.Introduction Immune checkpoint inhibitors, such as pembrolizumab, are increasingly used in high‐grade urothelial carcinomas. Immune checkpoint inhibitors are known to cause immune‐related adverse events (irAEs), often involving the skin. Case Presentation Reported is a 59‐year‐old woman with metastatic high‐grade urothelial carcinoma of the right renal
Matthew A. Drescher +3 more
wiley +1 more source
Case Reports in Rheumatology, Volume 2026, Issue 1, 2026.Systemic sclerosis (scleroderma) can manifest with advanced symptoms of ischemic vasculopathy, including digital ulcer development. These ulcerations can be disabling and detrimental to a patient’s quality of life, so prompt diagnosis, differentiation from other vascular etiologies, and treatment are important to help salvage this tissue.
Matthew Kornas +5 more
wiley +1 more source
Dermatologic Therapy, Volume 2026, Issue 1, 2026.Objective To characterize early clinical clues and diagnostic barriers in antimelanoma differentiation‐associated gene 5 dermatomyositis (MDA5‐DM), delineate real‐world misdiagnosis pathways, and propose practical diagnostic strategies and red‐flag features to improve timely recognition. Methods We retrospectively analyzed six consecutive patients with
Weiwei Shi +5 more
wiley +1 more source
Nailfold capillaroscopy in 430 patients with rheumatoid arthritis.
Caspian journal of internal medicine, 2017 Microvascular changes are one of the first obvious steps in numerous inflammatory diseases such as rheumatoid arthritis (RA). Nailfold video capillaroscopy (NFC) is an easy, reliable and safe method for evaluating peripheral microangiopathy. The objective of this study was to examine nailfold microcirculation in RA patients, assess morphological and ...
Rajaei, Alireza +2 more
openaire +3 more sources