Results 61 to 70 of about 4,588 (152)

Analysis of the Dynamics of Clinical Parameters and Serum Angiogenic Factors in Systemic Sclerosis Patients Undergoing Tocilizumab Treatment

open access: yesExperimental Dermatology, Volume 35, Issue 2, February 2026.
This study demonstrates that tocilizumab (TCZ) treatment promotes microvascular recovery in systemic sclerosis (SSc), as evidenced by increased capillary density and that this improvement in vasculopathy is closely associated with enhanced pulmonary function.
Yuichiro Segawa   +6 more
wiley   +1 more source

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

open access: yesArthritis Care &Research, Volume 78, Issue 1, Page 106-112, January 2026.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech   +4 more
wiley   +1 more source

Anti‐Eukaryotic Initiation Factor 2B‐Positive Systemic Sclerosis‐Associated Interstitial Lung Disease With Progressive Fibrosis: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We report the case of a patient with anti‐eIF2B‐positive SSc‐ILD managed with stepwise mycophenolate titration and subsequent nintedanib addition, accompanied by serial biomarkers and clinical follow‐up to help delineate the therapeutic course within this rare serological phenotype.
Hiro Ikeda   +3 more
wiley   +1 more source

Nailfold capillaroscopy: relevance to the practice of rheumatology [PDF]

open access: yes, 2015
Nailfold capillaroscopy is a simple, low-cost method, that is extremely important in the evaluation of patients with Raynaud's phenomenon and of patients with systemic sclerosis (SSc) spectrum diseases.
Kayser, Cristiane   +1 more
core   +1 more source

Clinical relevance of combining Thermography with Nailfold Capillaroscopy to improve differentiation between primary and secondary Raynaud's Phenomenon

open access: yes, 2021
Objectives: Early microvascular damage and dysfunction are clinically mirrored in Raynaud’s phenomenon (RP). Currently, nailfold capillaroscopy (NC) is applied to differentiate between primary RP (PRP) and secondary RP (PRP), associated with connective ...
Yumiko Vreeburg   +6 more
core   +1 more source

Periungual capillaroscopy in psoriasis Capilaroscopia periungueal em psoríase

open access: yesAnais Brasileiros de Dermatologia, 2012
BACKGROUND: Nailfold capillaroscopy is a useful technique for evaluating changes in microcirculation. OBJECTIVE: To investigate changes at nailfold capillaroscopy in psoriatic patients compared with controls.
Camila Ferrari Ribeiro   +4 more
doaj   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa   +7 more
wiley   +1 more source

Microvascular abnormalities in Sjogren's syndrome: nailfold capillaroscopy

open access: yes, 1999
Objective. To describe microvascular abnormalities by nailfold capillaroscopy in patients with primary Sjogren’s syndrome (SS) with or without Raynaud’s phenomenon (RP) and those with anticentromere antibodies (ACA). Methods.
Moutsopoulos, HM   +3 more
core   +1 more source

Vascular Endothelial Damage in COPD: Where Are We Now, Where Will We Go?

open access: yesDiagnostics
Background: Chronic obstructive pulmonary disease (COPD) has higher rates among the general population, so early identification and prevention is the goal.
Gianluca Screm   +11 more
doaj   +1 more source

Use of nailfold video capillaroscopy in polycythemia vera

open access: yesThe Turkish Journal of Gastroenterology, 2022
Objectives: In this study, we aimed to investigate capillary vessel diameters and structural changes of capillaries by using nailfold video capillaroscopy (NVC) in patients with polycythemia vera (PV). Patients and Methods: This cross-sectional study
Emine Duygu Ersozlu   +5 more
doaj  

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