Results 51 to 60 of about 13,887 (276)

Protein modification and maintenance systems as biomarkers of ageing [PDF]

, 2015
Changes in the abundance and post-translational modification of proteins and accumulation of some covalently modified proteins have been proposed to represent hallmarks of biological ageing.
Friguet, Bertrand, Gonos, Efstathios S, Libert, Claude, Petropoulos, Isabelle, Santos, Alexander Navarrete, Simm, Andreas, Vanhooren, Valerie, Voutetakis, Konstantinos   +7 more
core   +4 more sources

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Photochemical afterglow of single organic molecules with wide‐range tunable lifetime

PhotoMat, EarlyView., 2023
“All‐in‐one” strategy was used to achieve photochemical afterglow in single organic molecule, with second‐to‐hour range tunable lifetime by tailoring the electron‐withdrawing ability of substituents. Abstract Background Photochemical afterglow that relies on slow release of photons from the chemical energy stored by light pre‐irradiation has emerged as
Yuetian Pei, Yiwei Fan, Yawei Liu, Kuangshi Sun, Wei Feng, Qian Liu, Fuyou Li   +6 more
wiley   +1 more source

Naked mole rat (HETEROCEPHALUS GLABER)

BioScience, 2020
Abstract Enriching BioScience's role as a Forum for Integrating the Life Sciences, Arts in Science provides an occasional venue for poems, visual art, and other forms of artistic expression that explore and enliven our understanding of life.
openaire   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber

Вавиловский журнал генетики и селекции
DNA repair is a most important cellular process that helps maintain the integrity of the genome and is currently considered by researchers as one of the factors determining the maximum lifespan.
K. N. Naumenko, A. R. Nurislamov, K. D. Nazarov, V. S. Fishman, A. A. Popov, I. O. Petruseva, A. N. Evdokimov, O. I. Lavrik   +7 more
doaj   +1 more source

The Better to Eat You With: Bite Force in the Naked Mole-Rat (Heterocephalus glaber) Is Stronger Than Predicted Based on Body Size

Frontiers in Integrative Neuroscience, 2019
Naked mole-rats (Heterocephalus glaber) are subterranean rodents that utilize their incisors for feeding, chisel-tooth digging of complex tunnel systems, social interactions, and defense in their eusocial colony structure.
Natalee J. Hite, Cody Germain, Blake W. Cain, Mason Sheldon, Sai Saketh Nandan Perala, Diana K. Sarko   +5 more
doaj   +1 more source

Tactile sensing in the naked mole rat

Scholarpedia, 2015
Tactile sensing in the naked mole rat refers to the ability of this naturally blind species to respond to, and localize, stimuli that deflect facial vibrissae, but also an array of somatic vibrissae.
Christine M. Crish, Samuel D. Crish, Christopher Comer   +2 more
openaire   +1 more source

Oxidative stress and life histories: unresolved issues and current needs [PDF]

, 2015
Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details ...
Beaulieu, M., Blount, J.D., Briga, M., Bronikowski, A.M., Buffenstein, R., Carr, S.K., Christensen, L.L., Cocheme, H.M., Cram, D.L., Dantzer, B., Harper, J.M., Isaksson, C., Jurk, D., King, A., Kirkwood, T.B.L., Monaghan, P., Noguera, J.C., Ozanne, S.E., Peaker, M., Salin, K., Selman, C., Sild, E., Simons, M.J.P., Smith, S., Speakman, J.R., Stier, A., Tobler, M., Vitikainen, E.   +27 more
core   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source