Results 71 to 80 of about 835,919 (230)
Adult neurogenesis and its anatomical context in the hippocampus of three mole-rat species
Frontiers in Neuroanatomy, 2014 African mole-rats (family Bathyergidae) are small to medium sized, long-lived and strictly subterranean rodents that became valuable animal models as a result of their longevity and diversity in social organization.
Irmgard eAmrein +6 more
doaj +1 more source
A specialized cold sensing system in the naked mole-rat [PDF]
Avoiding cold or seeking warmth are universal animal needs. Homeothermic mammals maintain a constant body temperature despite fluctuating ambient temperatures. One exception is the naked mole-rat which lacks effective thermogenesis.
Wang L +10 more
europepmc +2 more sources
, 2021 Additional file 1: Tables S1 and S2. Sample details and respective TOS (total oxidant status), TAC (total antioxidant capacity) and OSI (oxidative stress index) for Naked mole-rats and for Damaraland mole-rats.
Paul Juan Jacobs (11451342) +2 more
core +1 more source
Advanced Science, EarlyView.Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang +11 more
wiley +1 more source
Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis
Advanced Science, EarlyView.Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran +10 more
wiley +1 more source
Extreme Resistance to Hypercapnia-Induced Pulmonary Edema of the African Naked Mole-Rat
, 2014 The African naked-mole rat lives chronically in a hypercapnia due to many individuals living together in small enclosed burrows. At extreme hypercapnia, pulmonary edema is induced in many terrestrial mammals.
Gregory R. Blass (7971221)
core +2 more sources
Advanced Science, EarlyView.High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang +11 more
wiley +1 more source
Photochemical afterglow of single organic molecules with wide‐range tunable lifetime
PhotoMat, EarlyView., 2023 “All‐in‐one” strategy was used to achieve photochemical afterglow in single organic molecule, with second‐to‐hour range tunable lifetime by tailoring the electron‐withdrawing ability of substituents. Abstract Background Photochemical afterglow that relies on slow release of photons from the chemical energy stored by light pre‐irradiation has emerged as
Yuetian Pei +6 more
wiley +1 more source
BioTechniques, 2010 Both emerging and well-established animal models are providing researchers novel insights into human biology. Diana Gitig explores new genetic approaches being used in the rat to uncover the basis of human disease and finds out just what the naked mole ...
Diana Gitig
doaj +1 more source
Advanced Science, EarlyView.CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai +15 more
wiley +1 more source