Results 21 to 30 of about 3,459 (225)

Behavioural Effects and Naloxone Effectiveness With New Synthetic Opioids. [PDF]

open access: yesDrug Alcohol Rev
ABSTRACT Introduction The global drug market has seen an emergence of potent synthetic opioids, including benzimidazole‐derived substances known as nitazenes. These compounds have been implicated in fatal and non‐fatal overdoses. This review aims to synthesise current evidence on the pharmacological effects, potency and naloxone responsiveness of new ...
Nielsen S   +8 more
europepmc   +2 more sources

THE EFFECT OF NALORPHINE ON THE ANTIDIURETIC ACTION OF MORPHINE IN RATS AND MEN [PDF]

open access: bronzeBritish Journal of Pharmacology and Chemotherapy, 1955
H. Schnieden, E. K. BLACKMORE
openalex   +2 more sources

Advances in the Physicochemical Profiling of Opioid Compounds of Therapeutic Interest. [PDF]

open access: yesChemistryOpen, 2019
Who is in charge? In solutions, naloxone exists in four differently charged forms. Its overall lipophilicity profile indicated by the broad black line is the sum of the contributions of its four forms. Although the non‐charged form of naloxone is less lipophilic than naltrexone, its relative concentration at physiological pH is higher.
Mazák K, Noszál B, Hosztafi S.
europepmc   +2 more sources

Beneficial Actions of Nalorphine during Hemorrhagic Shock in Cats

open access: closedExperimental Biology and Medicine, 1983
Endogenous opiates have been reported to have detrimental effects on the circulatory system during hemorrhagic shock. However, the specific opiate receptor subtype which mediates these actions has not been defined. In the present study, we have utilized the mixed agonist/antagonist, nalorphine (N-allylnormorphine), which exhibits kappa (kappa) and ...
C E, Hock   +3 more
openaire   +3 more sources

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander   +165 more
wiley   +1 more source

Hair testing applied to the assessment of in utero exposure to drugs: Critical analysis of 51 cases of the University Hospital of Verona

open access: yesDrug Testing and Analysis, Volume 15, Issue 9, Page 980-986, September 2023., 2023
Hair testing provides valuable and objective information on in utero drug exposure. To obtain a complete picture of the mother's addiction behaviour and of her family background, it is advisable to collect on the day of birth or the day after birth not only hair from the mother, newborn and father but also urine from the mother and newborn. Cocaine and
Anna Bertaso   +8 more
wiley   +1 more source

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