Results 1 to 10 of about 67,188 (308)

Nobody Wants to Be Narcan’d: A Pilot Qualitative Analysis of Drug Users’ Perspectives on Naloxone

Western Journal of Emergency Medicine, 2020
Introduction: Bystander naloxone distribution is an important component of public health initiatives to decrease opioid-related deaths. While there is evidence supporting naloxone distribution programs, the effects of increasing naloxone availability on ...
Jeffrey T. Lai, Charlotte E. Goldfine, Brittany P. Chapman, Melissa M. Taylor, Rochelle K. Rosen, Stephanie P. Carreiro, Kavita M. Babu   +6 more
doaj   +2 more sources

Preventing opioid overdose with peer-administered naloxone: findings from a rural state

Harm Reduction Journal, 2020
Background In response to the opioid epidemic, naloxone distribution programs aim to prevent overdose death by making naloxone available and training people to use it.
Bridget L. Hanson, Rebecca R. Porter, Amanda L. Zöld, Heather Terhorst-Miller   +3 more
doaj   +2 more sources

Take-home naloxone programs for suspected opioid overdose in community settings: a scoping umbrella review

BMC Public Health, 2021
Background Opioid related overdoses and overdose deaths continue to constitute an urgent public health crisis. The implementation of naloxone programs, such as ‘take-home naloxone’ (THN), has emerged as a key intervention in reducing opioid overdose ...
Amina Moustaqim-Barrette, Damon Dhillon, Justin Ng, Kristen Sundvick, Farihah Ali, Tara Elton-Marshall, Pamela Leece, Katherine Rittenbach, Max Ferguson, Jane A. Buxton   +9 more
doaj   +2 more sources

Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.

PLoS ONE, 2020
IntroductionOverdose is a leading cause of death in the United States, especially among people who inject drugs (PWID). Improving naloxone access and carrying among PWID may offset recent increases in overdose mortality associated with the influx of ...
Megan Buresh, Rachel E Gicquelais, Jacquie Astemborski, Gregory D Kirk, Shruti H Mehta, Becky L Genberg   +5 more
doaj   +2 more sources

Higher naloxone dosing in a quantitative systems pharmacology model that predicts naloxone-fentanyl competition at the opioid mu receptor level.

PLoS ONE, 2020
Rapid resuscitation of an opioid overdose with naloxone, an opioid antagonist, is critical. We developed an opioid receptor quantitative systems pharmacology (QSP) model for evaluation of naloxone dosing.
Ronald B Moss, Meghan McCabe Pryor, Rebecca Baillie, Katherine Kudrycki, Christina Friedrich, Mike Reed, Dennis J Carlo   +6 more
doaj   +2 more sources

Buprenorphine/naloxone – one formulation that doesn’t fit all: a case report [PDF]

Harm Reduction Journal
Background Sublingual buprenorphine, approved for treatment of opioid use disorder since 2002, is most commonly available in co-formulation with naloxone.
Hannan M. Braun, Jessica L. Taylor, Sarah Axelrath   +2 more
doaj   +2 more sources

The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews.

American Journal of Public Health, 2021
Background. Opioids contribute tomore than 60 000 deaths annually in North America. While the expansion of overdose education and naloxone distribution (OEND) programs has been recommended in response to the opioid crisis, their effectiveness remains ...
Amir Razaghizad, S. Windle, K. Filion, G. Gore, I. Kudrina, Elena Paraskevopoulos, J. Kimmelman, M. Martel, M. Eisenberg   +8 more
semanticscholar   +1 more source

Optimizing naloxone distribution to prevent opioid overdose fatalities: results from piloting the Systems Analysis and Improvement Approach within syringe service programs

BMC Health Services Research, 2023
Background Opioid overdose fatalities are preventable with timely administration of naloxone, an opioid antagonist, during an opioid overdose event. Syringe service programs have pioneered naloxone distribution for potential bystanders of opioid overdose.
Sheila V. Patel, Lynn D. Wenger, Alex H. Kral, Kenneth Sherr, Anjuli D. Wagner, Peter J. Davidson, Barrot H. Lambdin   +6 more
doaj   +1 more source

Practical implications of naloxone knowledge among suburban people who use opioids

Harm Reduction Journal, 2021
Background Naloxone distribution programs have been a cornerstone of the public health response to the overdose crisis in the USA. Yet people who use opioids (PWUO) continue to face a number of barriers accessing naloxone, including not knowing where it ...
Kristin E. Schneider, Glenna J. Urquhart, Saba Rouhani, Ju Nyeong Park, Miles Morris, Sean T. Allen, Susan G. Sherman   +6 more
doaj   +1 more source

Adverse events related to bystander naloxone administration in cases of suspected opioid overdose in British Columbia: An observational study.

PLoS ONE, 2021
IntroductionTake-Home Naloxone programs have been introduced across North America in response to rising opioid overdose deaths. There is currently limited real-world data on bystander naloxone administration, overdose outcomes, and evidence related to ...
Amina Moustaqim-Barrette, Kristi Papamihali, Sierra Williams, Max Ferguson, Jessica Moe, Roy Purssell, Jane A Buxton   +6 more
doaj   +2 more sources