Results 21 to 30 of about 101,541 (346)
PLACENTAL TRANSFER OF NALOXONE [PDF]
British Journal of Anaesthesia, 1986 Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m.
B.M. Hibbard, D. Davies, M. Rosen
openaire +4 more sources
Predicting pharmacy naloxone stocking and dispensing following a statewide standing order, Indiana 2016 [PDF]
, 2018 BACKGROUND: While naloxone, the overdose reversal medication, has been available for decades, factors associated with its availability through pharmacies remain unclear.
Agley, J.D. +8 more
core +1 more source
Harm Reduction Journal, 2022 Background Expanding availability to naloxone is a core harm reduction strategy in efforts to address the opioid epidemic. In the US, state-level legislation is a prominent mechanism to expand naloxone availability through various venues, such as ...
Sean Grant, Rosanna Smart
doaj +1 more source
Pharmacy, 2022 Background: Opioid overdoses continue to be one of the most urgent public health priorities. In 2020, reported overdose deaths in the United States reached a high of over 93,000 cases. As the COVID-19 pandemic and opioid crisis continues to be addressed,
Jennifer Courtney +6 more
doaj +1 more source
Homeless drug users' awareness and risk perception of peer "Take Home Naloxone" use – a qualitative study [PDF]
, 2006 BACKGROUND Peer use of take home naloxone has the potential to reduce drug related deaths. There appears to be a paucity of research amongst homeless drug users on the topic.
A Edwards +27 more
core +3 more sources
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog [PDF]
Eur J Pharmacol, 173174 (2020), 2020 Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on a molecular basis. Here, we examined the analgesic/adverse effect profile of a new NT(8-13) derivative denoted JMV2009, in which the Pro10 residue was substituted by a ...
arxiv +1 more source
Risk of respiratory depression with opioids and concomitant gabapentinoids. [PDF]
, 2017 Introduction:The combination of opioids and central nervous system depressants such as benzodiazepines and barbiturates has an additive effect on the frequency of oversedation and respiratory depression requiring naloxone use in hospitalized patients ...
Atayee, Rabia S +7 more
core +2 more sources
Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
, 2013 Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér +6 more
core +5 more sources
Prehospital naloxone administration – what influences choice of dose and route of administration?
BMC Emergency Medicine, 2020 Background Amidst the ongoing opioid crisis there are debates regarding the optimal route of administration and dosages of naloxone. This applies both for lay people administration and emergency medical services, and in the development of new naloxone ...
Ida Tylleskar +6 more
doaj +1 more source
Addiction, 2020 BACKGROUND AND AIMS Naloxone access laws (NALs) have been suggested as an important strategy to reduce opioid-related harm. We describe the evolution of NALs across states and over time and review existing evidence of their overall association with ...
Rosanna Smart, Bryce Pardo, C. Davis
semanticscholar +1 more source