Results 1 to 10 of about 22,974 (229)

Extemporaneous Preparation and Effectiveness of Low-Dose Naltrexone for the Treatment of Uremic Pruritus: A Literature Review and Case Report [PDF]

Pharmacy
Background: Uremic pruritus is one of the most debilitating complications among patients with end-stage kidney disease (ESKD) receiving hemodialysis.
Dhakrit Rungkitwattanakul, Michelle Brooks, Simeon Adesina, Sanaa Belrhiti, Weerachai Chaijamorn, Taniya Charoensareerat, Uzoamaka Nwaogwugwu, Constance Mere   +7 more
doaj   +2 more sources

Use of Naltrexone for Patients With Stimulant Use Disorder in Malaysia: Protocol for a Retrospective Cohort Study

JMIR Research Protocols
BackgroundNaltrexone is an opioid receptor antagonist. Naltrexone is used to block the euphoric and sedative effects of drugs such as heroin, codeine, and morphine.
Nor Asiah Muhamad, Nur Hasnah Ma'amor, Muhammad Arif Muhamad Rasat, Tengku Puteri Nadiah Tengku Baharudin Shah, 'Izzah 'Athirah Rosli, Fatin Norhasny Leman, Nurul Hidayah Jamalluddin, Nurul Syazwani Misnan, Norliza Chemi, Norni Abdullah, Nurashikin Ibrahim   +10 more
doaj   +2 more sources

Predicting individual treatment response in alcohol use disorders: a reverse translational proof-of-concept study [PDF]

Translational Psychiatry
The development of medications for alcohol use disorders (AUD) faces stagnation, as promising drugs failed to translate in clinic. Screening on homogeneous groups of animals drugs later tested on heterogeneous clinical cohorts may contribute to the ...
Sara De Carlo, Hela Mrizak, Andrea Della Valle, Veronica Lunerti, Manthoula O. Kyratzi, Alessandra Mammone, Antonio Lacorte, Adana Keshishian, Min Li, Esi Domi, Di Qin, Leah Solberg Woods, Laura Soverchia, Massimo Ubaldi, Roberto Ciccocioppo, Nazzareno Cannella   +15 more
doaj   +2 more sources

Demographic and Clinical Characteristics of 907 Cases with Naltrexone Intoxication; a 14-Year Cross-Sectional Study

Archives of Academic Emergency Medicine, 2022
Introduction: Opioids have been the leading cause of death from poisoning in Iran for several years. This study aimed to evaluate the clinical and para-clinical presentations of naltrexone intoxication, its toxic dose, and its epidemiological properties.
Mitra Rahimi, Alireza Kargar, Delara Hazegh Fetratjoo, Sayed Masoud Hosseini, Arezou Mahdavinejad, Shahin Shadnia   +5 more
doaj   +1 more source

Assessing Naltrexone Prescribing and Barriers to Initiation for Alcohol Use Disorder: A Multidisciplinary, Multisite Survey

Frontiers in Psychiatry, 2022
ObjectiveTo survey barriers in prescribing naltrexone for alcohol use disorder.MethodsA 12-question survey related to naltrexone prescribing patterns, perceptions, and knowledge was sent to 770 prescribers in the departments of internal medicine, family ...
Jonathan G. Leung, Prasanna P. Narayanan, Matej Markota, Nathaniel E. Miller, Kemuel L. Philbrick, M. Caroline Burton, Robert W. Kirchoff   +6 more
doaj   +1 more source

Maternally administered sustained-release naltrexone in rats affects offspring neurochemistry and behaviour in adulthood. [PDF]

PLoS ONE, 2012
Naltrexone is not recommended during pregnancy. However, sustained-release naltrexone implant use in humans has resulted in cases of inadvertent foetal exposure.
Waleed O Farid, Andrew J Lawrence, Elena V Krstew, Robert J Tait, Gary K Hulse, Sarah A Dunlop   +5 more
doaj   +1 more source

Naltrexone/bupropion for obesity: An investigational combination pharmacotherapy for weight loss

Pharmacological Research, 2014
Puspha Sinnayah, Michael A Cowley
exaly   +3 more sources

The effects of naltrexone on retention in treatment and being opioid-free in opioid-dependent people: A systematic review and meta-analysis

Frontiers in Psychiatry, 2022
BackgroundOpioid dependency is a chronic relapsing disorder for which different therapeutically interventions have been developed. Naltrexone is a non-selective opioid antagonist that can be utilized for maintenance therapy in opioid dependency.
Moein Zangiabadian, Saeid Golmohammadi, Seyed Aria Nejadghaderi, Mohammad Mahdi Zahmatkesh, Mohammad Javad Nasiri, Majid Sadeghian   +5 more
doaj   +1 more source

Naltrexone for alcohol use disorder: Hepatic safety in patients with and without liver disease

Hepatology Communications, 2022
Naltrexone is an approved drug for management of alcohol use disorder (AUD), but data in patients with liver disease (LD) are limited. We aimed to evaluate the safety of naltrexone in those with LD.
Divya Ayyala, Thomas Bottyan, Christine Tien, Michael Pimienta, Jennie Yoo, Kelli Stager, Jose Luis Gonzalez, Andrew Stolz, Jennifer L. Dodge, Norah A. Terrault, Hyosun Han   +10 more
doaj   +1 more source

Naltrexone aversion and treatment efficacy are greatest in humans and rats that actively consume high levels of alcohol

Neurobiology of Disease, 2009
The opioid antagonist naltrexone is the standard pharmacotherapy for alcoholism, although compliance is often low. The mechanism by which naltrexone reduces drinking is yet unclear.
Jennifer M. Mitchell, Lindsey J. Bergren, Katherine S. Chen, Michael C. Rowbotham, Howard L. Fields   +4 more
doaj   +1 more source