Results 91 to 100 of about 4,900 (222)

Formulation and corneal permeation of ketorolac tromethamine-loaded chitosan nanoparticles [PDF]

, 2016
The aim of this work was to formulate chitosan (CS)-based nanoparticles (NPs) loaded with ketorolac tromethamine (KT) intended for topical ocular delivery.
Amal K. Hussein, Anil Vangala, Karthikeyan D, Khaled A. Khaled, Lang JC, Raid G. Alany, Shankar C, Zeinab M. A. Fathalla, Zhou HY, Zhu X   +9 more
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Interactions of a Dopamine D Receptor Agonist with Glutamate NMDA Receptor Antagonists on the Volitional Consumption of Ethanol by the mHEP Rat [PDF]

, 2013
Stimulation of the dopamine D1 receptor is reported to cause the phosphorylation of DARPP-32 at the thre34 position and activates the protein. If intracellular Ca2+ is increased, such as after activation of the glutamate NMDA receptor, calcineurin ...
Brian McMillen, Cloninger, Courtney Lommatzsch, Davis, Gonzales, Helen Williams, Kranzler, Kranzler, Lovinger, Malpass, Malpass, Michael Sayonh, Morrisett, Myers, Myers, Risinger, Siggins, Zar   +17 more
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Investigation into the restoration of TRPM3 ion channel activity in post-COVID-19 condition: a potential pharmacotherapeutic target

Frontiers in Immunology
IntroductionRecently, we reported that post COVID-19 condition patients also have Transient Receptor Potential Melastatin 3 (TRPM3) ion channel dysfunction, a potential biomarker reported in natural killer (NK) cells from Myalgic Encephalomyelitis ...
Etianne Martini Sasso, Etianne Martini Sasso, Etianne Martini Sasso, Katsuhiko Muraki, Katsuhiko Muraki, Natalie Eaton-Fitch, Natalie Eaton-Fitch, Peter Smith, Peter Smith, Andrew Jeremijenko, Andrew Jeremijenko, Paul Griffin, Sonya Marshall-Gradisnik, Sonya Marshall-Gradisnik   +13 more
doaj   +1 more source

Living on the edge: Daily, seasonal and annual body temperature patterns of Arabian oryx in Saudi Arabia [PDF]

, 2017
Heterothermy, the ability to allow body temperature (Tb) to fluctuate, has been proposed as an adaptive mechanism that enables large ungulates to cope with the high environmental temperatures and lack of free water experienced in arid environments.
Alagaili, A, Bennett, Nigel, Bertelsen,, Ismael, K, Lutermann, H, Manger, Paul, Mohammed, Osama, Scantlebury, David, Streicher, S.   +8 more
core   +1 more source

Naltrexone Removal from Aqueous Media by Multi-Walled Carbon Nanotubes [PDF]

, 2016
Background: Extensive researches with different techniques are being carried out for removal of pharmaceuticals from aqueous media. The aim of this study was to use multi-walled carbon nanotubes (MWCNTs) to remove naltrexone as a pollutant of the aquatic
Ahmadi, Roushan, Ansari, Mehdi, Kazemipour, Maryam   +2 more
core  

Potential drug therapies for the treatment of fibromyalgia [PDF]

, 2016
INTRODUCTION: Fibromyalgia (FM) is a common, complex chronic widespread pain condition is characterized by fatigue, sleep disturbance and cognitive dysfunction.
Lawson, Kim
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Treatment of drug addiction and psychopathology: a field study [PDF]

, 2010
[Abstract] Field study to assess the concurrence of the psychopathology of drug addiction, and to evaluate the efficacy of pharmacological treatment versus drug-free treatments for the psychopathology of drug addiction.
Fernández-Ríos, Luis, Isorna, Manuel, Souto-Gestal, Antonio   +2 more
core   +3 more sources

A multicenter, primary care-based, open-label study to identify behaviors related to prescription opioid misuse, abuse, and diversion in opioid-experienced patients with chronic moderate-to-severe pain

Journal of Pain Research, 2015
Beatrice Setnik,1 Carl L Roland,1 Kenneth W Sommerville,1,2 Glenn C Pixton,1 Robert Berke,3,4 Anne Calkins,5 Veeraindar Goli1,2 1Pfizer Inc, 2Duke University Medical Center, Durham, NC, 3Family Health Medical Services PLLC, Mayville, NY, 4Department of ...
Setnik B, Rol, CL, Sommerville KW, Pixton GC, Berke R, Calkins A, Goli V   +7 more
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Experience with an extended-release opioid formulation designed to reduce abuse liability in a community-based pain management clinic

International Journal of General Medicine, 2011
Daniel Rubino Pain Center of Devon, Devon, PA, USA Context: With the growing public health concern over rising rates of opioid abuse, physicians have a responsibility to incorporate safeguards into their practice to minimize the potential for opioid ...
Rubino D
doaj  

Naltrexone-assisted rapid methadone discontinuation : a pilot study [PDF]

, 2009
Rapport de Synthèse : Un sevrage lent comme méthode élective pour l'interruption de la méthadone est coûteux en termes de temps, le plus souvent associé à un taux élevé d'abandon.
Camarasa Perez, J.
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