Saudi Pharmaceutical Journal, 2018 A rapid, simple and accurate micellar HPLC-method was adopted and validated for concurrent quantification of naltrexone hydrochloride (NTX) and bupropion hydrochloride (BUP).
Sherif A. Abdel-Gawad, Rania M. El-Gamal
doaj +1 more source
Journal of Translational Medicine, 2022 Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious disorder of unknown aetiology. While the pathomechanism of ME/CFS remains elusive, reduced natural killer (NK) cell cytotoxic function is a consistent immunological ...
Natalie Eaton-Fitch +5 more
doaj +1 more source
Evaluation of butorphanol, medetomidine and midazolam as a reversible narcotic combination in free-ranging African lions (Panthera leo) [PDF]
, 2010 Objective To evaluate the effects of the combination butorphanol, medetomidine and midazolam (BMM) and its reversibility in lions. Study design Prospective clinical trial.
Bush +37 more
core +1 more source
Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]
, 2020 Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib +3 more
core +2 more sources
PolyMorphine provides extended analgesic-like effects in mice with spared nerve injury. [PDF]
, 2017 Morphine is a well-characterized and effective analgesic commonly used to provide pain relief to patients suffering from both acute and chronic pain conditions.
Chen, Renxun +5 more
core +1 more source
Prazosin + Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in P Rats with a Protracted History of Extensive Voluntary Alcohol Drinking, Dependence, and Multiple Withdrawals [PDF]
, 2015 Background Prazosin (PRZ, an α1-adrenergic receptor antagonist) and naltrexone (NTX, a non-specific opioid receptor antagonist) each decrease alcohol drinking when administered to rats selectively-bred for high voluntary alcohol drinking (alcohol ...
Froehlich, Janice C. +2 more
core +1 more source
The use of thiafentanil oxalate and azaperone for reversible immobilisation of African buffalo (Syncerus caffer) within a nature reserve — Short communication [PDF]
, 2015 Although thiafentanil oxalate has been widely used for wildlife immobilisation on different species, no report has been published about its usefulness on African buffalo (Syncerus caffer).
Luyt, Eustatius +3 more
core +1 more source
Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors [PDF]
, 2017 Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to
Cannella, Nazzareno +3 more
core +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.SUMMARY A 17‐year‐old, 24‐kg, female greater rhea (Rhea americana) presented with an acute onset of left wing droop. Clinical examination and radiographs revealed an open, simple, displaced, short‐oblique diaphyseal fracture of the distal third of the left humerus.
Pierre Huberdeau +6 more
wiley +1 more source