Results 81 to 90 of about 4,900 (222)

Estimation of efficiency of double emulsification method for the preparation of naltrexone microspheres based on poly(lactic-co-glycolic acid) copolymer

Тонкие химические технологии, 2013
Administration of drug delivery systems allows reaching therapeutic efficiency in comparison with traditional dosage forms. Microspheres are used quite often as drug delivery systems in pharmaceutical technology.
E. A. Petrova, S. A. Kedik, K. V. Alekseev, E. V. Blynskaya, A. V. Panov, V. V. Suslov, N. V. Tikhonova   +6 more
doaj  

Pharmacological treatment of obesity: an overview of different groups of anti-obesity drugs available in Poland

Journal of Education, Health and Sport
Introduction and Objective: Obesity, as one of the diseases of civilization, has become a significant problem in our time. Although the first ways of treating it appeared many years ago, pharmacotherapy of obesity has been developing significantly in ...
Barbara Woch, Dawid Bereza, Katarzyna Sokołowska, Maria Kulak, Igor Moreau, Paulina Polańska, Miriam Lang   +6 more
doaj   +1 more source

Topiramate plus citalopram in the treatment of Compulsive-Impulsive Sexual Behaviors [PDF]

, 2006
Compulsive-Impulsive Sexual Behaviors (C-ISBs) include repetitive sexual acts and compulsive sexual thoughts which occur so frequently and with such intensity that they interfere with sexual intimacy and interpersonal and occupational functioning and ...
D. Marazziti, B. Dell'Osso
core   +1 more source

Recent Trends in the Development of Green Analytical Sample Preparation Methods Using Advanced Materials

Journal of Separation Science, Volume 48, Issue 5, May 2025.
ABSTRACT Recent concern about the impact of environmental preservation and the health of living beings has opened new avenues for scientific research. In this context, contemporary analytical chemistry has been marked by the development of green analytical methodologies, which aim to reduce the use of toxic reagents and minimize the environmental ...
Eduardo Carasek, Amanda Vitória Santos, Francielle Crocetta Turazzi, Lucas Morés, Luciane Effting, Guilherme Mariz de Oliveira Barra   +5 more
wiley   +1 more source

Molecular docking, molecular dynamics simulation, preparation, and characterization of naltrexone-phospholipid complex: A novel cargo with improved loading into multivesicular liposomes

Results in Chemistry
Naltrexone hydrochloride (NTX), a water-soluble opioid receptor antagonist, is prescribed widely for opioid and alcohol dependence and pain reduction. However, the significant limitations of NTX are low lipophilicity and extensive first-pass metabolism ...
Reihaneh Yousefi, Yasaman Rezaee, Fereshteh Bayat, Elham Rezaee, Leila Karami, Simin Dadashzadeh, Azadeh Haeri   +6 more
doaj   +1 more source

The Potential Use of Cannabidiol in the Treatment of Opioid Use Disorder: A Systematic Review

Addiction Biology, Volume 30, Issue 5, May 2025.
This systematic review found that CBD may reduce opioid cravings and abstinence‐related anxiety in individuals with opioid use disorder. Preclinical studies also suggest CBD can reduce withdrawal symptoms, opioid‐rewarding effects, relapse, and neuroinflammation.
Mahan Shafie, Kevin Ing, Yasna Rostam‐Abadi, Jeremy Weleff, Mackenzie Griffin, Mohini Ranganathan, Ardavan Mohammad Aghaei, Nicholas Pratt, Melissa C. Funaro, Anahita Bassir Nia   +9 more
wiley   +1 more source

Over the counter naloxone nasal spray: A new hope for opioid crisis management in Pakistan

Journal of the Pakistan Medical Association
Opioids, derived from the poppy plant, include synthetic and partially synthetic compounds that bind to brain receptors, diminishing pain perception. Primarily prescribed as analgesics, they are often misused for euphoria, thus making opioid overdose a ...
Zmarak Ahmed Khan, Zainab Anfaal, Muhammad Shaheer   +2 more
doaj   +1 more source

Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis [PDF]

, 2019
Background Naltrexone is an opioid antagonist used in many different conditions, both licensed and unlicensed. It is used at widely varying doses from 3 - 250 mg. The aim of this review was to evaluate the safety of oral naltrexone by examining the risk
A Hodkinson, A Roy, A Thompson, AK Traore, Alan Mould, Alex Hodkinson, B Afsharimani, BAC Cree, C Brewer, Center for Drug Evaluation and Research, Center for Biologics Evaluation and Research. Guidance for industry and investigators, D Dalton, D Moher, D Walters, DA Zarin, DE Jonas, DK Patten, DN Pfohl, European Commission, European Commission, European Commission, G Raknes, G Raknes, GA Diamond, GBD 2015 Disease and Injury Incidence and Prevalence Collaborators, GBD 2015 Mortality and Causes of Death Collaborators, Harm van Marwijk, ICH Harmonised Tripartite Guideline, Immune Therapeutics Inc. Immune Therapeutics, Inc, IS Zagon, J Budzyński, J Rehm, J Younger, JE Becker, JE Grant, JE Grant, JG Bramness, JJ Kirkham, JMA Sinclair, JP Ioannidis, JP Smith, JPA Ioannidis, K Kampman, K McPherson, K Papay, K Witkiewitz, KM Sturn, L Zorzela, LB Weinstock, Lisa Riste, LJ Dunlap, M McDonough, Maria Panagioti, MH Yen, MJ Page, MJ Sweeting, Monica Bolton, N Jayaram-Lindström, P Crowley, PA Spagnolo, PM Rothwell, PN Papanikolaou, R Pryce, RA Johnson, RS Croop, S Cao, S Derry, S Rösner, S-E Brown, Sarah Rhodes, Shivani Boda, SS O’Malley, YK Loke, YK Loke, Z Yi   +73 more
core   +4 more sources

Thermosensitive Pluronic® hydrogel: prolonged injectable formulation for drug abuse

Drug Design, Development and Therapy, 2010
Katayoun Derakhshandeh1, Mahtab Fashi1, Seyedalireza Seifoleslami21Department of Pharmaceutics, Faculty of Pharmacy, University of Medical Science, Kermanshah; 2Research and Development Department, Forensic Medicine Organization, Kermanshah ...
Katayoun Derakhshandeh, Mahtab Fashi, Seyedalireza Seifoleslami   +2 more
doaj  

An Exploratory Study of Suboxone (Buprenorphine/ Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability [PDF]

, 2019
Suboxone films are U.S. Food and Drug Administration approved to treat opioid dependence. While the package insert states that films should not be cut, physicians often prescribe film fractions for treatment and tapering. There is no data to support this
Conn, Kelly, Corigliano, Anthony, DeAngelis, Michael J., Ferrara, Alexander S., Phillips, Elizabeth, Reindel, Kristin L., Zhao, Fang   +6 more
core   +1 more source