Results 121 to 130 of about 15,085 (211)
Oncology Reports, 2011 Nicotinamide phosphoribosyltransferase (Nampt), an enzyme involved in the NAD⁺ salvage pathway, is over-expressed and important in the carcinogenesis in several types of cancers. The expression of Nampt and its role in gastric cancer remain largely unknown. In this study, using real-time PCR and Western blotting we found that Nampt was overexpressed at
Tie-Qiang, Bi +6 more
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High NAMPT expression and anti-tumour activity of NAMPT inhibitor in adult T-cell leukemia/lymphoma
Annals of Oncology, 2019 Abstract Background Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature T lymphocytes induced by human T-cell leukemia virus-1, and has a poor outcome. New molecular targets for the prevention and treatment of ATL are urgently needed.
T. Kozako +8 more
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Thiazolocarboxamide Analogues as NAMPT Inhibitors [PDF]
ACS Medicinal Chemistry Letters, 2014 Jean-Francois, Brazeau, Gerard, Rosse
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Mediators of Inflammation, 2015 Nampt/visfatin acts in both intracellular and extracellular compartments to regulate multiple biological roles, including NAD metabolism, cancer, inflammation, and senescence.
Yi-Ching Lin +5 more
doaj +1 more source
NAMPT regulates mitochondria and oxidative stress level for mouse early embryo development
Biological ResearchBackground Nicotinamide phosphoribosyltransferase (NAMPT) is an enzyme that involves into NMN-NAD + synthesis which involves into cellular metabolism related with aging, immune function, and neurodegeneration.
Mei-Hua Liao +7 more
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The Faculty Notebook, April 2010
, 2010 The Faculty Notebook is published periodically by the Office of the Provost at Gettysburg College to bring to the attention of the campus community accomplishments and activities of academic interest.
Provost\u27s Office,
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Omentin-1, visfatin and adiponectin levels in relation to bone mineral density in Iranian postmenopausal women [PDF]
, 2012 The bone and fat interface is implicated in the pathogenesis of postmenopausal osteoporosis. The association between circulating omentin-1 levels and bone mineral density (BMD) in postmenopausal women has never been assessed.
Akbarzadeh, Samad +10 more
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Communications BiologyNicotinamide phosphoribosyltransferase (NAMPT) plays an important role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+) via the nicotinamide (NAM) salvage pathway. While the structural biochemistry of eukaryote NAMPT has been well studied,
Guolyu Xu +12 more
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Structural elements determining NAMPT activity
, 2023 Nikotinamidadenindinukleotid (NAD) er en hydridbærer involvert i redoksreaksjoner i metabolismen. I tillegg er NAD+ et substrat av enzymer som medierer vitale NAD+-avhengige prosesser, der dinukleotidet spaltes, og frigjør en nikotinamiddel (Nam). Vedlikehold av disse prosessene krever en kontinuerlig påfyll av NAD, som hovedsakelig gjøres av Nam ...
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Serum visfatin and vaspin levels in normoglycemic first-degree relatives of Iranian patients with type 2 diabetes mellitus [PDF]
, 2011 Aim: To investigate circulating visfatin and vaspin levels in first-degree relatives of subjects with type 2 diabetes mellitus (FDRs) who frequently have higher value of HOMA-IR and beta cell dysfunction.
Akbarzadeh, Samad +6 more
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