Results 181 to 190 of about 19,910 (273)

Streptavidin-biotin-based directional double Nanobody sandwich ELISA for clinical rapid and sensitive detection of influenza H5N1 [PDF]

, 2014

core   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Single-domain antibodies for brain targeting [PDF]

, 2014
Lalatsa, Katerina, Moreira Leite, Diana
core   +1 more source

Monitoring and Managing of Ergot Alkaloids in Cereal Grains: A Comprehensive Analysis of Analytical Challenges, Sampling Uncertainty, and Processing for Food Safety

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Ergot alkaloids (EAs), toxic secondary metabolites produced by Claviceps purpurea, pose food and feed safety concerns for cereal grains, particularly rye and wheat. While EAs are most frequently associated with rye, their occurrence in other cereals has been increasingly reported across diverse regions.
Chamali Kodikara, Nandika Bandara, Sheryl A. Tittlemier   +2 more
wiley   +1 more source

Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. [PDF]

Nat Commun
Aagaard JB, Gandini R, Ballegaard AR, Jensen BK, Dorn B, Larsen AVB, Lenstrup A, Sønderholm M, Miehe M, Pfützner W, Jakob T, Andersen GR, Möbs C, Spillner E.   +13 more
europepmc   +1 more source

HSP-1-specific nanobodies alter chaperone function in vitro and in vivo. [PDF]

J Biol Chem
Urban ND, Gharat K, Mattiola ZJ, Scheutzow A, Klaiss A, Tabler S, Huffaker AW, Grootveld M, Skinner ME, Zheng W, O'Meara MJ, Kirstein J, Truttmann MC.   +12 more
europepmc   +1 more source

Quantitative Mapping of Nanoscale EGFR–Grb2 Assemblies by DNA‐PAINT

ChemPhysChem, Volume 27, Issue 8, 28 April 2026.
Single‐molecule DNA‐PAINT imaging resolves the nanoscale organization of epidermal growth factor receptor (EGFR) and the adaptor protein Grb2 in cells. An analysis workflow quantitatively reports EGF‐induced EGFR reorganization, increased oligomerization, and progressive Grb2 recruitment at individual membrane‐protein assembly sites.Receptor tyrosine ...
Alexandra Kaminer, Yunqing Li, Hans‐Dieter Barth, Marina S. Dietz, Mike Heilemann   +4 more
wiley   +1 more source

Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies. [PDF]

Proc Natl Acad Sci U S A
Barilone N, Vangelatou M, Marouf FZ, Dejean de la Bâtie G, Li Q, Lafaye P, Aymé G, Corringer PJ, Prevost MS.   +8 more
europepmc   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

<i>Alpseq</i>: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing. [PDF]

MAbs
Zeglinski K, Schuster J, Sa JD, Adair A, Deng J, Pymm P, Ritchie ME, Bowden R, Tham WH, Gouil Q.   +9 more
europepmc   +1 more source