Results 171 to 180 of about 11,503 (243)

Intracellularly delivered nanobody targeting the nucleocapsid protein effectively inhibits porcine deltacoronavirus replication. [PDF]

Vet Res
Hou C, Liu L, Kang R, Liu S, Sun Y, Chu Q, Lei C, Wang H, Yang X.   +8 more
europepmc   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Pfs48/45 nanobodies block Plasmodium falciparum transmission. [PDF]

PLoS Pathog
Lyons FMT, Chmielewski J, Gabriela M, Chan LJ, Tong J, Adair A, Zeglinski K, Gouil Q, Dietrich MH, Tham WH.   +9 more
europepmc   +1 more source

Enhancing the sensitivity of nanobodies through covalent and non-covalent polymerization. [PDF]

RSC Adv
Wang F, Chen J, Chen JH, Liu XM, Hu LQ, Huo LJ.   +5 more
europepmc   +1 more source

Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen. [PDF]

Nat Commun
Aagaard JB, Gandini R, Ballegaard AR, Jensen BK, Dorn B, Larsen AVB, Lenstrup A, Sønderholm M, Miehe M, Pfützner W, Jakob T, Andersen GR, Möbs C, Spillner E.   +13 more
europepmc   +1 more source

HSP-1-specific nanobodies alter chaperone function in vitro and in vivo. [PDF]

J Biol Chem
Urban ND, Gharat K, Mattiola ZJ, Scheutzow A, Klaiss A, Tabler S, Huffaker AW, Grootveld M, Skinner ME, Zheng W, O'Meara MJ, Kirstein J, Truttmann MC.   +12 more
europepmc   +1 more source

Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies. [PDF]

Proc Natl Acad Sci U S A
Barilone N, Vangelatou M, Marouf FZ, Dejean de la Bâtie G, Li Q, Lafaye P, Aymé G, Corringer PJ, Prevost MS.   +8 more
europepmc   +1 more source

Surface Plasmon Resonance (SPR) Workflow for Comparative Analysis of Nanobody Variants Binding to Lysozyme as a Model Ligand. [PDF]

Curr Protoc
Díaz-Galicia E, Gutu N, Peng Y, Valitova A, Renn D, Rueping M.   +5 more
europepmc   +1 more source

A simple and broadly applicable nanobody-based approach to generate potent TNFR agonists. [PDF]

Cell Death Dis
Lang I, Zaitseva O, Glöckler A, Siegmund D, Sheta D, Mouhandes B, Weisenberger D, Schäfer V, Stepanzow S, Schneider T, Beilhack A, Crauel A, Kilisch M, Funk LM, Götzke H, Frey S, Wajant H.   +16 more
europepmc   +1 more source

Translational opportunities in aptamer and nanobody lateral flow assays within the WHO REASSURED framework.

Sens Diagn
Monk ET, McConnell EM, McMullin DR, DeRosa MC.   +3 more
europepmc   +1 more source